Application of miR-29a-Exosome and multifunctional scaffold for full-thickness cartilage defects

Background: Full-thickness cartilage defect is a common refractory disease in orthopedics. In this study, we designed a novel composite scaffold composed of silk fibroin-chitosan for the cartilage layer and porous tantalum for the subchondral bone layer, loaded with engineered bone mesenchymal stem...

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Bibliographic Details
Main Authors: Fan Yang, Zewen Wang, Mingjian Wu, Jingyi Xu, Junlei Li, Jiahe Liu, Ting He, Tao Zhang, Baoyi Liu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Extracellular Vesicle
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Online Access:http://www.sciencedirect.com/science/article/pii/S2773041724000222
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