New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils

The incidence of ulcerative colitis has been increasing in recent years, and its manifestation at a young age has become a trend that is prognostically unfavorable. The clinical picture of ulcerative colitis is often vague, which leads to an initially erroneous diagnosis. One of the main problems is...

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Main Authors: E. V. Bolotova, K. A. Yumukyan, A. V. Dudnikova
Format: Article
Language:Russian
Published: SINAPS LLC 2022-08-01
Series:Архивъ внутренней медицины
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Online Access:https://www.medarhive.ru/jour/article/view/1481
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author E. V. Bolotova
K. A. Yumukyan
A. V. Dudnikova
author_facet E. V. Bolotova
K. A. Yumukyan
A. V. Dudnikova
author_sort E. V. Bolotova
collection DOAJ
description The incidence of ulcerative colitis has been increasing in recent years, and its manifestation at a young age has become a trend that is prognostically unfavorable. The clinical picture of ulcerative colitis is often vague, which leads to an initially erroneous diagnosis. One of the main problems is to assess the effectiveness of treatment and the risk of recurrence of ulcerative colitis, which requires invasive intervention. The aim of the study was to analyze the data of modern scientific literature on noninvasive biomarkers of ulcerative colitis. The data of foreign and domestic articles on the research topic published in Pubmed and eLibrary over the past 5-10 years are analyzed. Biomarkers of neutrophil origin are a promising direction in the primary diagnosis and assessment of ulcerative colitis activity.
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institution Kabale University
issn 2226-6704
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publisher SINAPS LLC
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series Архивъ внутренней медицины
spelling doaj-art-a1b43ea4ac6947f39cc47d5ac17c13552025-08-20T03:37:56ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642022-08-0112428529210.20514/2226-6704-2022-12-4-285-292903New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of NeutrophilsE. V. Bolotova0K. A. Yumukyan1A. V. Dudnikova2State budgetary educational institution of higher professional education «Kuban state medical university» Ministry of health of the Russian FederationState budgetary educational institution of higher professional education «Kuban state medical university» Ministry of health of the Russian Federation; State Public Health Budget Institution Scientific Research Institute — Ochapovsky Regional Clinic Hospital of Krasnodar Region Public Health MinistryState budgetary educational institution of higher professional education «Kuban state medical university» Ministry of health of the Russian FederationThe incidence of ulcerative colitis has been increasing in recent years, and its manifestation at a young age has become a trend that is prognostically unfavorable. The clinical picture of ulcerative colitis is often vague, which leads to an initially erroneous diagnosis. One of the main problems is to assess the effectiveness of treatment and the risk of recurrence of ulcerative colitis, which requires invasive intervention. The aim of the study was to analyze the data of modern scientific literature on noninvasive biomarkers of ulcerative colitis. The data of foreign and domestic articles on the research topic published in Pubmed and eLibrary over the past 5-10 years are analyzed. Biomarkers of neutrophil origin are a promising direction in the primary diagnosis and assessment of ulcerative colitis activity.https://www.medarhive.ru/jour/article/view/1481ulcerative colitisinflammatory bowel diseasesneutrophilsnoninvasive biomarkers
spellingShingle E. V. Bolotova
K. A. Yumukyan
A. V. Dudnikova
New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils
Архивъ внутренней медицины
ulcerative colitis
inflammatory bowel diseases
neutrophils
noninvasive biomarkers
title New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils
title_full New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils
title_fullStr New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils
title_full_unstemmed New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils
title_short New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils
title_sort new diagnostic possibilities for determining the activity of ulcerative colitis the role of neutrophils
topic ulcerative colitis
inflammatory bowel diseases
neutrophils
noninvasive biomarkers
url https://www.medarhive.ru/jour/article/view/1481
work_keys_str_mv AT evbolotova newdiagnosticpossibilitiesfordeterminingtheactivityofulcerativecolitistheroleofneutrophils
AT kayumukyan newdiagnosticpossibilitiesfordeterminingtheactivityofulcerativecolitistheroleofneutrophils
AT avdudnikova newdiagnosticpossibilitiesfordeterminingtheactivityofulcerativecolitistheroleofneutrophils