Bacteriophage–derived double-stranded RNA (larifan) exerts variable effects on human blood monocytes depending on age and sex of donors

Bacteriophage–derived double-stranded RNA (larifan) exerts variable effects on human blood monocytes depending on age and sex of donors

To date, great attention is paid to sex and age differences in the therapeutic effectiveness of drugs, including those that impact the immune system. Bacteriophage-derived dsRNA is the main component of the medicinal product Larifan, which exhibits interferonogenic activity. This study aimed to esti...

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Bibliographic Details
Main Authors: R. Dovhyi, M. Rudyk, T. Serhiichuk, Yu. Yumyna, A. Dvukhriadkina, K. Ostrovska, D. Pjanova, L. Skivka
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2024-10-01
Series:The Ukrainian Biochemical Journal
Subjects:
double-stranded rna
larifan
monocytes
phagocytosis
reactive oxygen species
sex and age differences
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2024/10/Dovhyi_96_5.pdf
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