In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus

Luromarin, extracted from the sea alga Zostera asiatica, showed no cytotoxic activity when incubated with the SPEV cell culture and was characterized by virulicidal properties against highly pathogenic strain of TBE virus and the ability to inhibit the virus replication at the early stages of the in...

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Main Authors: N. V. Krylova, G. N. Leonova, O. S. Maistrovskaya, A. M. Popov, A. A. Artyukov, E. P. Kozlovskaya
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
Subjects:
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/317
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author N. V. Krylova
G. N. Leonova
O. S. Maistrovskaya
A. M. Popov
A. A. Artyukov
E. P. Kozlovskaya
author_facet N. V. Krylova
G. N. Leonova
O. S. Maistrovskaya
A. M. Popov
A. A. Artyukov
E. P. Kozlovskaya
author_sort N. V. Krylova
collection DOAJ
description Luromarin, extracted from the sea alga Zostera asiatica, showed no cytotoxic activity when incubated with the SPEV cell culture and was characterized by virulicidal properties against highly pathogenic strain of TBE virus and the ability to inhibit the virus replication at the early stages of the infection.
format Article
id doaj-art-a1ab598610bc46a482ccfa36000faaa9
institution Kabale University
issn 0235-2990
language Russian
publishDate 2020-05-01
publisher LLC "Publishing House OKI"
record_format Article
series Антибиотики и Химиотерапия
spelling doaj-art-a1ab598610bc46a482ccfa36000faaa92025-08-20T03:42:01ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01557-8316In vitro Activity of Luromarin Against Tick-Borne Encephalitis VirusN. V. Krylova0G. N. Leonova1O. S. Maistrovskaya2A. M. Popov3A. A. Artyukov4E. P. Kozlovskaya5Research Institute of Epidemiology and Microbiology of the Siberian Branch of the Russian Academy of Medical SciencesResearch Institute of Epidemiology and Microbiology of the Siberian Branch of the Russian Academy of Medical SciencesResearch Institute of Epidemiology and Microbiology of the Siberian Branch of the Russian Academy of Medical SciencesPacific Institute of Bioorganic Chemistry, Ear-East Branch of the Russian Academy of SciencesPacific Institute of Bioorganic Chemistry, Ear-East Branch of the Russian Academy of SciencesPacific Institute of Bioorganic Chemistry, Ear-East Branch of the Russian Academy of SciencesLuromarin, extracted from the sea alga Zostera asiatica, showed no cytotoxic activity when incubated with the SPEV cell culture and was characterized by virulicidal properties against highly pathogenic strain of TBE virus and the ability to inhibit the virus replication at the early stages of the infection.https://www.antibiotics-chemotherapy.ru/jour/article/view/317tick-borne encephalitisrosmarinic acidantiviral activity
spellingShingle N. V. Krylova
G. N. Leonova
O. S. Maistrovskaya
A. M. Popov
A. A. Artyukov
E. P. Kozlovskaya
In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus
Антибиотики и Химиотерапия
tick-borne encephalitis
rosmarinic acid
antiviral activity
title In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus
title_full In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus
title_fullStr In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus
title_full_unstemmed In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus
title_short In vitro Activity of Luromarin Against Tick-Borne Encephalitis Virus
title_sort in vitro activity of luromarin against tick borne encephalitis virus
topic tick-borne encephalitis
rosmarinic acid
antiviral activity
url https://www.antibiotics-chemotherapy.ru/jour/article/view/317
work_keys_str_mv AT nvkrylova invitroactivityofluromarinagainsttickborneencephalitisvirus
AT gnleonova invitroactivityofluromarinagainsttickborneencephalitisvirus
AT osmaistrovskaya invitroactivityofluromarinagainsttickborneencephalitisvirus
AT ampopov invitroactivityofluromarinagainsttickborneencephalitisvirus
AT aaartyukov invitroactivityofluromarinagainsttickborneencephalitisvirus
AT epkozlovskaya invitroactivityofluromarinagainsttickborneencephalitisvirus