A meta-analysis on the role of sonication in the diagnosis of cardiac implantable electronic device-related infections
IntroductionOne of the biggest obstacles in diagnosing Implant-Associated Infections is the lack of infection criteria and standardized diagnostic methods. These infections present a wide range of symptoms, and their diagnosis can be hampered by the formation of microbial biofilms on the surface of...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-03-01
|
| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2024.1361626/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825197111959879680 |
|---|---|
| author | Daniela Araújo João P. Martins João P. Martins Stephanie Lopes Ferreira Stephanie Lopes Ferreira Sandra Mota Sandra Mota Pedro L. Ferreira Pedro L. Ferreira Rui Pimenta Rui Pimenta |
| author_facet | Daniela Araújo João P. Martins João P. Martins Stephanie Lopes Ferreira Stephanie Lopes Ferreira Sandra Mota Sandra Mota Pedro L. Ferreira Pedro L. Ferreira Rui Pimenta Rui Pimenta |
| author_sort | Daniela Araújo |
| collection | DOAJ |
| description | IntroductionOne of the biggest obstacles in diagnosing Implant-Associated Infections is the lack of infection criteria and standardized diagnostic methods. These infections present a wide range of symptoms, and their diagnosis can be hampered by the formation of microbial biofilms on the surface of implants. This study aimed to provide insight into the performance of sonication in the diagnosis of infections associated with Cardiac Implantable Electronic Devices, to help define a consensus on the algorithm for the microbial diagnosis of these infections.MethodsWe carried out a systematic review with meta-analysis. The PRISMA methodology guidelines were followed, and an advanced search was carried out in PubMed and Web of Science, which enabled 8 articles to be included in the review, in which a meta-analysis was also carried out. QUADAS-2 was used to assess the risk of bias and effect measures were calculated to assess publication bias.ResultsThe overall sensitivity of the method was 0.823 (95% CI: 0.682–0.910) and the specificity was 0.632 (95% CI: 0.506–0.743).DiscussionThese results suggest that sonication may offer advantages in diagnosing these infections. However, it is essential to approach these findings carefully and take into account the recommendations provided in the EHRA 2019 guidelines. This study highlights the importance of more effective diagnostic approaches for implantable medical device-associated infections to improve the quality of treatment and minimize the risks associated with these challenging medical conditions. |
| format | Article |
| id | doaj-art-a1a1f7b49d2443a58fc2bea45e2a99b7 |
| institution | Kabale University |
| issn | 1664-302X |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj-art-a1a1f7b49d2443a58fc2bea45e2a99b72025-02-11T18:59:02ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2024-03-011510.3389/fmicb.2024.13616261361626A meta-analysis on the role of sonication in the diagnosis of cardiac implantable electronic device-related infectionsDaniela Araújo0João P. Martins1João P. Martins2Stephanie Lopes Ferreira3Stephanie Lopes Ferreira4Sandra Mota5Sandra Mota6Pedro L. Ferreira7Pedro L. Ferreira8Rui Pimenta9Rui Pimenta10Escola Superior de Saúde, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, Porto, PortugalEscola Superior de Saúde, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, Porto, PortugalCEAUL– Centro de Estatística e Aplicações, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, Lisbon, PortugalEscola Superior de Saúde, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, Porto, PortugalCHUdSA – Centro Hospitalar Universitário de Santo António, Porto, PortugalEscola Superior de Saúde, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, Porto, PortugalREQUIMTE/LAQV, Escola Superior de Saúde, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, Porto, PortugalFaculty of Economics, University of Coimbra, Coimbra, PortugalCentre for Health Studies and Research of University of Coimbra, Centre for Innovative Biomedicine and Biotechnology, Avenida Dias da Silva, Coimbra, PortugalEscola Superior de Saúde, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, Porto, PortugalCentre for Health Studies and Research of University of Coimbra, Centre for Innovative Biomedicine and Biotechnology, Avenida Dias da Silva, Coimbra, PortugalIntroductionOne of the biggest obstacles in diagnosing Implant-Associated Infections is the lack of infection criteria and standardized diagnostic methods. These infections present a wide range of symptoms, and their diagnosis can be hampered by the formation of microbial biofilms on the surface of implants. This study aimed to provide insight into the performance of sonication in the diagnosis of infections associated with Cardiac Implantable Electronic Devices, to help define a consensus on the algorithm for the microbial diagnosis of these infections.MethodsWe carried out a systematic review with meta-analysis. The PRISMA methodology guidelines were followed, and an advanced search was carried out in PubMed and Web of Science, which enabled 8 articles to be included in the review, in which a meta-analysis was also carried out. QUADAS-2 was used to assess the risk of bias and effect measures were calculated to assess publication bias.ResultsThe overall sensitivity of the method was 0.823 (95% CI: 0.682–0.910) and the specificity was 0.632 (95% CI: 0.506–0.743).DiscussionThese results suggest that sonication may offer advantages in diagnosing these infections. However, it is essential to approach these findings carefully and take into account the recommendations provided in the EHRA 2019 guidelines. This study highlights the importance of more effective diagnostic approaches for implantable medical device-associated infections to improve the quality of treatment and minimize the risks associated with these challenging medical conditions.https://www.frontiersin.org/articles/10.3389/fmicb.2024.1361626/fullsonicationimplant associated infectionscardiac implantable electronic devicesbiofilmsmicrobiological diagnosissystematic review |
| spellingShingle | Daniela Araújo João P. Martins João P. Martins Stephanie Lopes Ferreira Stephanie Lopes Ferreira Sandra Mota Sandra Mota Pedro L. Ferreira Pedro L. Ferreira Rui Pimenta Rui Pimenta A meta-analysis on the role of sonication in the diagnosis of cardiac implantable electronic device-related infections Frontiers in Microbiology sonication implant associated infections cardiac implantable electronic devices biofilms microbiological diagnosis systematic review |
| title | A meta-analysis on the role of sonication in the diagnosis of cardiac implantable electronic device-related infections |
| title_full | A meta-analysis on the role of sonication in the diagnosis of cardiac implantable electronic device-related infections |
| title_fullStr | A meta-analysis on the role of sonication in the diagnosis of cardiac implantable electronic device-related infections |
| title_full_unstemmed | A meta-analysis on the role of sonication in the diagnosis of cardiac implantable electronic device-related infections |
| title_short | A meta-analysis on the role of sonication in the diagnosis of cardiac implantable electronic device-related infections |
| title_sort | meta analysis on the role of sonication in the diagnosis of cardiac implantable electronic device related infections |
| topic | sonication implant associated infections cardiac implantable electronic devices biofilms microbiological diagnosis systematic review |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2024.1361626/full |
| work_keys_str_mv | AT danielaaraujo ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT joaopmartins ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT joaopmartins ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT stephanielopesferreira ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT stephanielopesferreira ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT sandramota ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT sandramota ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT pedrolferreira ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT pedrolferreira ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT ruipimenta ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT ruipimenta ametaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT danielaaraujo metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT joaopmartins metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT joaopmartins metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT stephanielopesferreira metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT stephanielopesferreira metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT sandramota metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT sandramota metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT pedrolferreira metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT pedrolferreira metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT ruipimenta metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections AT ruipimenta metaanalysisontheroleofsonicationinthediagnosisofcardiacimplantableelectronicdevicerelatedinfections |