Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomas
896 patients (pts) with malignant non-Hodgkin's lymphomas were examined in this study. Т-cell immunophenotype has been established in 208 cases. Diagnosis was established according to the WHO criteria. We used the panel from 15 monoclonal antibodies for the detailed characteristic of Т-cell imm...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2022-11-01
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| Series: | Онкогематология |
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| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/607 |
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| author | I. B. Kovynev T. I. Pospelova E. N. Voropaeva N. J. Djachkova N. V. Skvortsova A. S. Ljamkina I. N. Nechunaeva |
| author_facet | I. B. Kovynev T. I. Pospelova E. N. Voropaeva N. J. Djachkova N. V. Skvortsova A. S. Ljamkina I. N. Nechunaeva |
| author_sort | I. B. Kovynev |
| collection | DOAJ |
| description | 896 patients (pts) with malignant non-Hodgkin's lymphomas were examined in this study. Т-cell immunophenotype has been established in 208 cases. Diagnosis was established according to the WHO criteria. We used the panel from 15 monoclonal antibodies for the detailed characteristic of Т-cell immunophenotype of non-Hodgkin's lymphomas. Lymphoblastic lymphomas was revealed in 115 pts and peripheral T-lymphomas in 93 pts. It was shown, that immunocytochemical research with quantitative calculation of antigen-positive cells has the certain value for differential diagnostics of peripheral Tcell lymphomas. We determined some quantitative diagnostics criteria in addition to WHO classification and proved their evidence in malignancy heterogeneity typical for T-cell lymphomas. |
| format | Article |
| id | doaj-art-a19b2a17ec6a49d4a8354699c5768942 |
| institution | DOAJ |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| publishDate | 2022-11-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj-art-a19b2a17ec6a49d4a8354699c57689422025-08-20T03:21:28ZrusABV-pressОнкогематология1818-83462413-40232022-11-010391410.17650/1818-8346-2007-0-3-9-14485Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomasI. B. Kovynev0T. I. Pospelova1E. N. Voropaeva2N. J. Djachkova3N. V. Skvortsova4A. S. Ljamkina5I. N. Nechunaeva6Novosibirsk state medical universityNovosibirsk state medical universityNovosibirsk state medical universityCity haematologic center of the mayoralty of NovosibirskNovosibirsk state medical universityNovosibirsk state medical universityCity haematologic center of the mayoralty of Novosibirsk896 patients (pts) with malignant non-Hodgkin's lymphomas were examined in this study. Т-cell immunophenotype has been established in 208 cases. Diagnosis was established according to the WHO criteria. We used the panel from 15 monoclonal antibodies for the detailed characteristic of Т-cell immunophenotype of non-Hodgkin's lymphomas. Lymphoblastic lymphomas was revealed in 115 pts and peripheral T-lymphomas in 93 pts. It was shown, that immunocytochemical research with quantitative calculation of antigen-positive cells has the certain value for differential diagnostics of peripheral Tcell lymphomas. We determined some quantitative diagnostics criteria in addition to WHO classification and proved their evidence in malignancy heterogeneity typical for T-cell lymphomas.https://oncohematology.abvpress.ru/ongm/article/view/607non-hodgkin's t-cell lymphomasclassification of t-cell neoplasmsadditional quantitative immunocytochemical criteria |
| spellingShingle | I. B. Kovynev T. I. Pospelova E. N. Voropaeva N. J. Djachkova N. V. Skvortsova A. S. Ljamkina I. N. Nechunaeva Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomas Онкогематология non-hodgkin's t-cell lymphomas classification of t-cell neoplasms additional quantitative immunocytochemical criteria |
| title | Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomas |
| title_full | Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomas |
| title_fullStr | Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomas |
| title_full_unstemmed | Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomas |
| title_short | Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomas |
| title_sort | additional diagnostic immunocytochemical criteria for t nk cell lymphomas |
| topic | non-hodgkin's t-cell lymphomas classification of t-cell neoplasms additional quantitative immunocytochemical criteria |
| url | https://oncohematology.abvpress.ru/ongm/article/view/607 |
| work_keys_str_mv | AT ibkovynev additionaldiagnosticimmunocytochemicalcriteriafortnkcelllymphomas AT tipospelova additionaldiagnosticimmunocytochemicalcriteriafortnkcelllymphomas AT envoropaeva additionaldiagnosticimmunocytochemicalcriteriafortnkcelllymphomas AT njdjachkova additionaldiagnosticimmunocytochemicalcriteriafortnkcelllymphomas AT nvskvortsova additionaldiagnosticimmunocytochemicalcriteriafortnkcelllymphomas AT asljamkina additionaldiagnosticimmunocytochemicalcriteriafortnkcelllymphomas AT innechunaeva additionaldiagnosticimmunocytochemicalcriteriafortnkcelllymphomas |