Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)Sensors

Silsesquioxanes (SSQs) comprise an interesting and versatile class of three-dimensional organosilicate oligomers with diverse structural arrangements and interesting physicochemical properties. SSQs are of considerable technological interest, with applications that include the development of electro...

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Main Authors: Felipe Zahrebelnei, Ariane Caroline Ribicki, Aline Martins Duboc Natal, Sérgio Toshio Fujiwara, Karen Wohnrath, Dhésmon Lima, Christiana Andrade Pessôa
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Chemosensors
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Online Access:https://www.mdpi.com/2227-9040/12/12/259
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author Felipe Zahrebelnei
Ariane Caroline Ribicki
Aline Martins Duboc Natal
Sérgio Toshio Fujiwara
Karen Wohnrath
Dhésmon Lima
Christiana Andrade Pessôa
author_facet Felipe Zahrebelnei
Ariane Caroline Ribicki
Aline Martins Duboc Natal
Sérgio Toshio Fujiwara
Karen Wohnrath
Dhésmon Lima
Christiana Andrade Pessôa
author_sort Felipe Zahrebelnei
collection DOAJ
description Silsesquioxanes (SSQs) comprise an interesting and versatile class of three-dimensional organosilicate oligomers with diverse structural arrangements and interesting physicochemical properties. SSQs are of considerable technological interest, with applications that include the development of electrochemical detection devices. The presence of functional groups on their structures enables the anchoring of different electroactive and conductive species, such as complexes, metal nanoparticles and carbon nanomaterials, and biomolecules, including enzymes, nucleic acids, and antibodies, which boosts the sensitivity and selectivity of the obtained (bio)sensors. These materials can also be incorporated into conductive matrices using a range of methods, which enhances their versatility. This mini review provides an overview of the most recent applications of hybrid organic–inorganic SSQs in the preparation of modified electrodes for the development of electrochemical sensors and biosensors. Special focus is placed on the incorporation of nanomaterials in their polymeric structure and on the design and fabrication of electrochemical devices using different strategies.
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publishDate 2024-12-01
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series Chemosensors
spelling doaj-art-a19a5c6a66ab4464bdab50c8116513f42025-08-20T02:53:33ZengMDPI AGChemosensors2227-90402024-12-01121225910.3390/chemosensors12120259Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)SensorsFelipe Zahrebelnei0Ariane Caroline Ribicki1Aline Martins Duboc Natal2Sérgio Toshio Fujiwara3Karen Wohnrath4Dhésmon Lima5Christiana Andrade Pessôa6Department of Chemistry, Universidade Estadual de Ponta Grossa, Avenida General Carlos Cavalcanti 4748, Ponta Grossa 84030-900, PR, BrazilDepartment of Chemistry, Universidade Estadual de Ponta Grossa, Avenida General Carlos Cavalcanti 4748, Ponta Grossa 84030-900, PR, BrazilDepartment of Chemistry, Universidade Estadual de Ponta Grossa, Avenida General Carlos Cavalcanti 4748, Ponta Grossa 84030-900, PR, BrazilDepartment of Chemistry, Universidade Estadual de Ponta Grossa, Avenida General Carlos Cavalcanti 4748, Ponta Grossa 84030-900, PR, BrazilDepartment of Chemistry, Universidade Estadual de Ponta Grossa, Avenida General Carlos Cavalcanti 4748, Ponta Grossa 84030-900, PR, BrazilDepartment of Chemistry and Physics, Mount Saint Vincent University, 166 Bedford Highway, Halifax, NS B3M 2J6, CanadaDepartment of Chemistry, Universidade Estadual de Ponta Grossa, Avenida General Carlos Cavalcanti 4748, Ponta Grossa 84030-900, PR, BrazilSilsesquioxanes (SSQs) comprise an interesting and versatile class of three-dimensional organosilicate oligomers with diverse structural arrangements and interesting physicochemical properties. SSQs are of considerable technological interest, with applications that include the development of electrochemical detection devices. The presence of functional groups on their structures enables the anchoring of different electroactive and conductive species, such as complexes, metal nanoparticles and carbon nanomaterials, and biomolecules, including enzymes, nucleic acids, and antibodies, which boosts the sensitivity and selectivity of the obtained (bio)sensors. These materials can also be incorporated into conductive matrices using a range of methods, which enhances their versatility. This mini review provides an overview of the most recent applications of hybrid organic–inorganic SSQs in the preparation of modified electrodes for the development of electrochemical sensors and biosensors. Special focus is placed on the incorporation of nanomaterials in their polymeric structure and on the design and fabrication of electrochemical devices using different strategies.https://www.mdpi.com/2227-9040/12/12/259silsesquioxanesmodified electrodeselectrochemical sensorsbiosensorsnanomaterialsvoltammetry
spellingShingle Felipe Zahrebelnei
Ariane Caroline Ribicki
Aline Martins Duboc Natal
Sérgio Toshio Fujiwara
Karen Wohnrath
Dhésmon Lima
Christiana Andrade Pessôa
Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)Sensors
Chemosensors
silsesquioxanes
modified electrodes
electrochemical sensors
biosensors
nanomaterials
voltammetry
title Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)Sensors
title_full Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)Sensors
title_fullStr Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)Sensors
title_full_unstemmed Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)Sensors
title_short Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)Sensors
title_sort silsesquioxanes as promising materials for the development of electrochemical bio sensors
topic silsesquioxanes
modified electrodes
electrochemical sensors
biosensors
nanomaterials
voltammetry
url https://www.mdpi.com/2227-9040/12/12/259
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