Left Ventricular Assist Device (LVAD)-Related Major Adverse Events Account for a Low Number of Emergency Room Admissions in HeartMate 3™ Patients—A 10-Year Retrospective Study
<b>Background:</b> The yearly number of left ventricular assist device (LVAD) implantations is approximately twice the number of heart transplantations (HTX) in Germany. As the number of patients with an LVAD installed grows, so does the likelihood of their presentation to the emergency...
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2025-07-01
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| author | Christoph Salewski Christian Jörg Rustenbach Spiros Lukas Marinos Rodrigo Sandoval Boburg Christian Schlensak Medhat Radwan |
| author_facet | Christoph Salewski Christian Jörg Rustenbach Spiros Lukas Marinos Rodrigo Sandoval Boburg Christian Schlensak Medhat Radwan |
| author_sort | Christoph Salewski |
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| description | <b>Background:</b> The yearly number of left ventricular assist device (LVAD) implantations is approximately twice the number of heart transplantations (HTX) in Germany. As the number of patients with an LVAD installed grows, so does the likelihood of their presentation to the emergency room (ER). Due to uneasiness in identifying their primary complaint, ER personnel are often likely to overlook important clues in the treatment of patients with an LVAD. <b>Methods:</b> To assess the urgency of patients’ conditions and their relationship with LVADs, we retrospectively examined the ER admissions of patients with HeartMate 3<sup>TM</sup> (HM 3) LVADs installed between 2014 and 2024 at our university medical center. We counted referrals to the peripheral ward (minor) and to the intensive care unit (ICU, major). Relation to LVAD relation was also recorded. The survival was analyzed with respect to the severity of the cause of admission (minor/major) and the relationship to the LVAD therapy. <b>Results:</b> We observed 100 presentations to the emergency department. Of these, 77 were minor and 23 were major. The majority (92) was not related to the LVAD. Of the eight admissions related to the LVAD, two were major adverse events, accounting only for 2% of the total cases. <b>Conclusions:</b> An ER presentation of a patient with an HM 3 is very likely to have a medical cause not related to the LVAD. LVAD-related causes were mostly minor and could be treated on the ward. |
| format | Article |
| id | doaj-art-a196506157df466e8caa5202cd3c638d |
| institution | DOAJ |
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| publishDate | 2025-07-01 |
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| spelling | doaj-art-a196506157df466e8caa5202cd3c638d2025-08-20T03:04:42ZengMDPI AGBiomedicines2227-90592025-07-01137170210.3390/biomedicines13071702Left Ventricular Assist Device (LVAD)-Related Major Adverse Events Account for a Low Number of Emergency Room Admissions in HeartMate 3™ Patients—A 10-Year Retrospective StudyChristoph Salewski0Christian Jörg Rustenbach1Spiros Lukas Marinos2Rodrigo Sandoval Boburg3Christian Schlensak4Medhat Radwan5Department of Thoracic and Cardiovascular Surgery, University Hospital Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, GermanyDepartment of Thoracic and Cardiovascular Surgery, University Hospital Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, GermanyDepartment of Thoracic and Cardiovascular Surgery, University Hospital Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, GermanyDepartment of Thoracic and Cardiovascular Surgery, University Hospital Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, GermanyDepartment of Thoracic and Cardiovascular Surgery, University Hospital Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, GermanyDepartment of Thoracic and Cardiovascular Surgery, University Hospital Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, Germany<b>Background:</b> The yearly number of left ventricular assist device (LVAD) implantations is approximately twice the number of heart transplantations (HTX) in Germany. As the number of patients with an LVAD installed grows, so does the likelihood of their presentation to the emergency room (ER). Due to uneasiness in identifying their primary complaint, ER personnel are often likely to overlook important clues in the treatment of patients with an LVAD. <b>Methods:</b> To assess the urgency of patients’ conditions and their relationship with LVADs, we retrospectively examined the ER admissions of patients with HeartMate 3<sup>TM</sup> (HM 3) LVADs installed between 2014 and 2024 at our university medical center. We counted referrals to the peripheral ward (minor) and to the intensive care unit (ICU, major). Relation to LVAD relation was also recorded. The survival was analyzed with respect to the severity of the cause of admission (minor/major) and the relationship to the LVAD therapy. <b>Results:</b> We observed 100 presentations to the emergency department. Of these, 77 were minor and 23 were major. The majority (92) was not related to the LVAD. Of the eight admissions related to the LVAD, two were major adverse events, accounting only for 2% of the total cases. <b>Conclusions:</b> An ER presentation of a patient with an HM 3 is very likely to have a medical cause not related to the LVAD. LVAD-related causes were mostly minor and could be treated on the ward.https://www.mdpi.com/2227-9059/13/7/1702LVADHeartMate3<sup>TM</sup>emergency roomacute adverse events |
| spellingShingle | Christoph Salewski Christian Jörg Rustenbach Spiros Lukas Marinos Rodrigo Sandoval Boburg Christian Schlensak Medhat Radwan Left Ventricular Assist Device (LVAD)-Related Major Adverse Events Account for a Low Number of Emergency Room Admissions in HeartMate 3™ Patients—A 10-Year Retrospective Study Biomedicines LVAD HeartMate3<sup>TM</sup> emergency room acute adverse events |
| title | Left Ventricular Assist Device (LVAD)-Related Major Adverse Events Account for a Low Number of Emergency Room Admissions in HeartMate 3™ Patients—A 10-Year Retrospective Study |
| title_full | Left Ventricular Assist Device (LVAD)-Related Major Adverse Events Account for a Low Number of Emergency Room Admissions in HeartMate 3™ Patients—A 10-Year Retrospective Study |
| title_fullStr | Left Ventricular Assist Device (LVAD)-Related Major Adverse Events Account for a Low Number of Emergency Room Admissions in HeartMate 3™ Patients—A 10-Year Retrospective Study |
| title_full_unstemmed | Left Ventricular Assist Device (LVAD)-Related Major Adverse Events Account for a Low Number of Emergency Room Admissions in HeartMate 3™ Patients—A 10-Year Retrospective Study |
| title_short | Left Ventricular Assist Device (LVAD)-Related Major Adverse Events Account for a Low Number of Emergency Room Admissions in HeartMate 3™ Patients—A 10-Year Retrospective Study |
| title_sort | left ventricular assist device lvad related major adverse events account for a low number of emergency room admissions in heartmate 3™ patients a 10 year retrospective study |
| topic | LVAD HeartMate3<sup>TM</sup> emergency room acute adverse events |
| url | https://www.mdpi.com/2227-9059/13/7/1702 |
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