Isolation and purification of Huperzine A

Technique of isolation and purification of Huperzine A from Huperzia serrata (Thunb) Trev. was studied in this paper. To get rid of some pigments and other impurities, some of chemical techniques for separation such as extraction with organic acid, absorption with charcol and re-crystallization with...

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Main Authors: SHEN Sheng-rong, Yu Hai-ning, JIN Chao-fang, XU Yue-rong
Format: Article
Language:English
Published: Zhejiang University Press 2002-11-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/1008-9209.2002.06.0591
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author SHEN Sheng-rong
Yu Hai-ning
JIN Chao-fang
XU Yue-rong
author_facet SHEN Sheng-rong
Yu Hai-ning
JIN Chao-fang
XU Yue-rong
author_sort SHEN Sheng-rong
collection DOAJ
description Technique of isolation and purification of Huperzine A from Huperzia serrata (Thunb) Trev. was studied in this paper. To get rid of some pigments and other impurities, some of chemical techniques for separation such as extraction with organic acid, absorption with charcol and re-crystallization with chloroform were employed. The results suggested that: ① pH value seriously influenced Huperzine A in solution; ② There are ideal procedures with extraction under the certain environment of pH value; ③ Charcol plays an important role in the process; ④ The measurement of re-crystallization had crucial role in promoting the purity of Huperzine A.
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issn 1008-9209
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language English
publishDate 2002-11-01
publisher Zhejiang University Press
record_format Article
series 浙江大学学报. 农业与生命科学版
spelling doaj-art-a1918cd54cbc4441bec50c4c97d515be2025-08-20T03:15:38ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552002-11-012859159510.3785/1008-9209.2002.06.059110089209Isolation and purification of Huperzine ASHEN Sheng-rongYu Hai-ningJIN Chao-fangXU Yue-rongTechnique of isolation and purification of Huperzine A from Huperzia serrata (Thunb) Trev. was studied in this paper. To get rid of some pigments and other impurities, some of chemical techniques for separation such as extraction with organic acid, absorption with charcol and re-crystallization with chloroform were employed. The results suggested that: ① pH value seriously influenced Huperzine A in solution; ② There are ideal procedures with extraction under the certain environment of pH value; ③ Charcol plays an important role in the process; ④ The measurement of re-crystallization had crucial role in promoting the purity of Huperzine A.https://www.academax.com/doi/10.3785/1008-9209.2002.06.0591Huperzine AextractionpurificationpHeffect
spellingShingle SHEN Sheng-rong
Yu Hai-ning
JIN Chao-fang
XU Yue-rong
Isolation and purification of Huperzine A
浙江大学学报. 农业与生命科学版
Huperzine A
extraction
purification
pH
effect
title Isolation and purification of Huperzine A
title_full Isolation and purification of Huperzine A
title_fullStr Isolation and purification of Huperzine A
title_full_unstemmed Isolation and purification of Huperzine A
title_short Isolation and purification of Huperzine A
title_sort isolation and purification of huperzine a
topic Huperzine A
extraction
purification
pH
effect
url https://www.academax.com/doi/10.3785/1008-9209.2002.06.0591
work_keys_str_mv AT shenshengrong isolationandpurificationofhuperzinea
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AT jinchaofang isolationandpurificationofhuperzinea
AT xuyuerong isolationandpurificationofhuperzinea