Development of an automated, high-throughput SARS-CoV-2 neutralization assay based on a pseudotyped virus using a vesicular stomatitis virus (VSV) vector

Development of an automated, high-throughput SARS-CoV-2 neutralization assay based on a pseudotyped virus using a vesicular stomatitis virus (VSV) vector

The global outbreak of COVID-19 has caused a severe threat to human health; therefore, simple, high-throughput neutralization assays are desirable for developing vaccines and drugs against COVID-19. In this study, a high-titre SARS-CoV-2 pseudovirus was successfully packaged by truncating the C-term...

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Bibliographic Details
Main Authors: Ziteng Liang, Xi Wu, Jiajing Wu, Shuo Liu, Jincheng Tong, Tao Li, Yuanling Yu, Li Zhang, Chenyan Zhao, Qiong Lu, Haiyang Qin, Jianhui Nie, Weijin Huang, Youchun Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
VSV
pseudovirus
neutralization assay
high-throughput
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2261566
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