Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeutics

Over the past decade, the evolution of magnetic nanoparticles as propitious materials in the area of detection of cancer and their treatment was accomplished with magnetic resonance imaging methods and other sensing techniques. In cancer research, the special properties of magnetic nanoparticles are...

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Main Authors: Pratima Devi Sivasubramanian, Gayathri Unnikrishnan, Elayaraja Kolanthai, Senthilkumar Muthuswamy
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Next Materials
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949822824003022
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author Pratima Devi Sivasubramanian
Gayathri Unnikrishnan
Elayaraja Kolanthai
Senthilkumar Muthuswamy
author_facet Pratima Devi Sivasubramanian
Gayathri Unnikrishnan
Elayaraja Kolanthai
Senthilkumar Muthuswamy
author_sort Pratima Devi Sivasubramanian
collection DOAJ
description Over the past decade, the evolution of magnetic nanoparticles as propitious materials in the area of detection of cancer and their treatment was accomplished with magnetic resonance imaging methods and other sensing techniques. In cancer research, the special properties of magnetic nanoparticles are intensively investigated in order to deliver medicines to a specific area via a modified, in vivo, external magnetic field operation. Furthermore, customized anticancer treatment in combination with imaging methods to achieve systematic treatment is discussed. In comparison to previous review articles, this review article provides an overview of compounds composed of metal ions or clusters that are linked to organic ligands to form various dimensional structures, as well as the interaction of tumour cells spreading in the primary site. This research gives a good insight into cutting-edge research on a variety of tumor-related topics, such as the clonal evolution theory, the use of magnetic nanoparticles in cancer diagnosis, treatment, targeted drug delivery agents, and metal organic frameworks for treating cancers as well as future developments in the field of oncology.
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spelling doaj-art-a183262bb7b947af9c2e0d5841bb1a7c2025-08-20T03:16:35ZengElsevierNext Materials2949-82282025-01-01610040510.1016/j.nxmate.2024.100405Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeuticsPratima Devi Sivasubramanian0Gayathri Unnikrishnan1Elayaraja Kolanthai2Senthilkumar Muthuswamy3Centre for Nanoscience and Genomics, Karunya Institute of Technology and Sciences, Coimbatore, India; Centre for Environmental Sustainability and Human Health, Ming Chi University of Technology, New Taipei City 24301, TaiwanDepartment of Physics, Karunya Institute of Technology and Sciences, Coimbatore, IndiaAdvanced Materials Processing and Analysis Centre, Department of Materials Engineering and Computer Sciences, University of Central Florida, Orlando, FL, USA; Corresponding author.Department of Physics, Karunya Institute of Technology and Sciences, Coimbatore, India; Correspondence to: Department of Physics, School of Science Arts, Media and Management, Karunya Institute of Technology and Sciences, Coimbatore, India.Over the past decade, the evolution of magnetic nanoparticles as propitious materials in the area of detection of cancer and their treatment was accomplished with magnetic resonance imaging methods and other sensing techniques. In cancer research, the special properties of magnetic nanoparticles are intensively investigated in order to deliver medicines to a specific area via a modified, in vivo, external magnetic field operation. Furthermore, customized anticancer treatment in combination with imaging methods to achieve systematic treatment is discussed. In comparison to previous review articles, this review article provides an overview of compounds composed of metal ions or clusters that are linked to organic ligands to form various dimensional structures, as well as the interaction of tumour cells spreading in the primary site. This research gives a good insight into cutting-edge research on a variety of tumor-related topics, such as the clonal evolution theory, the use of magnetic nanoparticles in cancer diagnosis, treatment, targeted drug delivery agents, and metal organic frameworks for treating cancers as well as future developments in the field of oncology.http://www.sciencedirect.com/science/article/pii/S2949822824003022Magnetic nanoparticlesCancer treatmentClonal evolution theoryMetal organic frameworksTargeted drug delivery
spellingShingle Pratima Devi Sivasubramanian
Gayathri Unnikrishnan
Elayaraja Kolanthai
Senthilkumar Muthuswamy
Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeutics
Next Materials
Magnetic nanoparticles
Cancer treatment
Clonal evolution theory
Metal organic frameworks
Targeted drug delivery
title Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeutics
title_full Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeutics
title_fullStr Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeutics
title_full_unstemmed Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeutics
title_short Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeutics
title_sort engineered nanoparticle systems a review on emerging strategies for enhanced cancer therapeutics
topic Magnetic nanoparticles
Cancer treatment
Clonal evolution theory
Metal organic frameworks
Targeted drug delivery
url http://www.sciencedirect.com/science/article/pii/S2949822824003022
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AT elayarajakolanthai engineerednanoparticlesystemsareviewonemergingstrategiesforenhancedcancertherapeutics
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