Symptomatic Giant Skene’s Gland Cyst During Second Trimester Pregnancy and Surgical Excision: A Case Report

<b>Introduction:</b> A Skene’s gland cyst is a rare gynecological disorder, and the cause of an adult onset is largely unknown. However, periurethral and perineal cystic lesions are common, causing often indistinguishable symptoms. Therefore, accurate diagnosis is crucial because it can...

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Main Authors: Brinkley Cover, Juliana Tovar, Omosiuwa L. Enakpene, Christopher A. Enakpene
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Reproductive Medicine
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Online Access:https://www.mdpi.com/2673-3897/5/4/27
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author Brinkley Cover
Juliana Tovar
Omosiuwa L. Enakpene
Christopher A. Enakpene
author_facet Brinkley Cover
Juliana Tovar
Omosiuwa L. Enakpene
Christopher A. Enakpene
author_sort Brinkley Cover
collection DOAJ
description <b>Introduction:</b> A Skene’s gland cyst is a rare gynecological disorder, and the cause of an adult onset is largely unknown. However, periurethral and perineal cystic lesions are common, causing often indistinguishable symptoms. Therefore, accurate diagnosis is crucial because it can significantly alter clinical management. <b>Methods</b>: A 27-year-old woman was gravida 2 para 1 with the onset of a unique, progressively large vulvar mass that began at approximately 6 weeks of gestation. At 22 weeks of gestation, the mass became more symptomatic and measured approximately 9 cm × 7 cm × 6 cm in size, with some areas of excoriation on the lateral surface. <b>Results:</b> The patient had a pelvic MRI without contrast, and it showed that the mass was most likely a giant Skene’s gland cyst. At 24 weeks, the mass was surgically removed under spinal anesthesia and followed by vulvar reconstruction. Histopathology showed a benign cyst lined by transitional and squamous epithelium cells, which was consistent with a benign Skene’s gland cyst. She recovered fully, continued with the pregnancy and delivered vaginally at 39 weeks and 3 days without complications. <b>Conclusions:</b> A case of excoriating giant Skene’s gland cyst in pregnancy that caused significant discomfort to the patient. To this day, there has been no reported literature of a Skene’s gland cyst this large, especially during pregnancy. Hence, Skene’s gland cysts should be part of the differential diagnosis of a large vulvar mass of this magnitude during pregnancy.
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spelling doaj-art-a1722f0b8388478fbcc01995ea8e956e2025-08-20T02:39:41ZengMDPI AGReproductive Medicine2673-38972024-12-015431031810.3390/reprodmed5040027Symptomatic Giant Skene’s Gland Cyst During Second Trimester Pregnancy and Surgical Excision: A Case ReportBrinkley Cover0Juliana Tovar1Omosiuwa L. Enakpene2Christopher A. Enakpene3Department of OBGYN, Permian Basin Campus, College of Medicine, Texas Tech University Health Sciences Center, Odessa, TX 79763, USADepartment of Family Medicine, Lubbock Campus, College of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79763, USADepartment of Psychology and Neurosciences, College of Literature, Sciences and Arts, University of Michigan, Ann Abort, MI 48104, USAMaternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, School of Medicine, Texas Tech University Health Sciences Center, Odessa, TX 79763, USA<b>Introduction:</b> A Skene’s gland cyst is a rare gynecological disorder, and the cause of an adult onset is largely unknown. However, periurethral and perineal cystic lesions are common, causing often indistinguishable symptoms. Therefore, accurate diagnosis is crucial because it can significantly alter clinical management. <b>Methods</b>: A 27-year-old woman was gravida 2 para 1 with the onset of a unique, progressively large vulvar mass that began at approximately 6 weeks of gestation. At 22 weeks of gestation, the mass became more symptomatic and measured approximately 9 cm × 7 cm × 6 cm in size, with some areas of excoriation on the lateral surface. <b>Results:</b> The patient had a pelvic MRI without contrast, and it showed that the mass was most likely a giant Skene’s gland cyst. At 24 weeks, the mass was surgically removed under spinal anesthesia and followed by vulvar reconstruction. Histopathology showed a benign cyst lined by transitional and squamous epithelium cells, which was consistent with a benign Skene’s gland cyst. She recovered fully, continued with the pregnancy and delivered vaginally at 39 weeks and 3 days without complications. <b>Conclusions:</b> A case of excoriating giant Skene’s gland cyst in pregnancy that caused significant discomfort to the patient. To this day, there has been no reported literature of a Skene’s gland cyst this large, especially during pregnancy. Hence, Skene’s gland cysts should be part of the differential diagnosis of a large vulvar mass of this magnitude during pregnancy.https://www.mdpi.com/2673-3897/5/4/27Skene’s gland cystpregnancyMRIsurgical excisionvaginal delivery
spellingShingle Brinkley Cover
Juliana Tovar
Omosiuwa L. Enakpene
Christopher A. Enakpene
Symptomatic Giant Skene’s Gland Cyst During Second Trimester Pregnancy and Surgical Excision: A Case Report
Reproductive Medicine
Skene’s gland cyst
pregnancy
MRI
surgical excision
vaginal delivery
title Symptomatic Giant Skene’s Gland Cyst During Second Trimester Pregnancy and Surgical Excision: A Case Report
title_full Symptomatic Giant Skene’s Gland Cyst During Second Trimester Pregnancy and Surgical Excision: A Case Report
title_fullStr Symptomatic Giant Skene’s Gland Cyst During Second Trimester Pregnancy and Surgical Excision: A Case Report
title_full_unstemmed Symptomatic Giant Skene’s Gland Cyst During Second Trimester Pregnancy and Surgical Excision: A Case Report
title_short Symptomatic Giant Skene’s Gland Cyst During Second Trimester Pregnancy and Surgical Excision: A Case Report
title_sort symptomatic giant skene s gland cyst during second trimester pregnancy and surgical excision a case report
topic Skene’s gland cyst
pregnancy
MRI
surgical excision
vaginal delivery
url https://www.mdpi.com/2673-3897/5/4/27
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AT omosiuwalenakpene symptomaticgiantskenesglandcystduringsecondtrimesterpregnancyandsurgicalexcisionacasereport
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