Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum
Scedosporium/Pseudallescheria species are frequently seen in cystic fibrosis patients. However, disseminated forms after lung transplantation in these patients are rarely seen, but often with poor outcome. In this case report we...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2011/460313 |
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| author | B. Luijk M. B. Ekkelenkamp P. A. De Jong J. M. Kwakkel-van Erp J. C. Grutters D. A. van Kessel E. A. van de Graaf |
| author_facet | B. Luijk M. B. Ekkelenkamp P. A. De Jong J. M. Kwakkel-van Erp J. C. Grutters D. A. van Kessel E. A. van de Graaf |
| author_sort | B. Luijk |
| collection | DOAJ |
| description | Scedosporium/Pseudallescheria species are frequently seen in
cystic fibrosis patients. However, disseminated forms after lung
transplantation in these patients are rarely seen, but often with
poor outcome. In this case report we describe a lung transplant
recipient with cystic fibrosis who developed a spondylodiscitis
that was caused by Scedosporium apiospermum. The patient was
treated with anti-fungal treatment by voriconazole for over three
years with a clinical good response and without the need for
surgical intervention. To our opinion this is the first
anti-fungal treated case of invasive disease caused by
Scedosporium/Pseudallescheria in a cystic fibrosis (CF) patient
who underwent lung transplantation that survived. |
| format | Article |
| id | doaj-art-a169af95c55c47aab3f28d46641a5a18 |
| institution | OA Journals |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-a169af95c55c47aab3f28d46641a5a182025-08-20T02:20:09ZengWileyCase Reports in Infectious Diseases2090-66252090-66332011-01-01201110.1155/2011/460313460313Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermumB. Luijk0M. B. Ekkelenkamp1P. A. De Jong2J. M. Kwakkel-van Erp3J. C. Grutters4D. A. van Kessel5E. A. van de Graaf6Division of Heart and Lungs, Departments of Respiratory Medicine and Lung Transplantation, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The NetherlandsDepartment of Clinical Microbiology, University Medical Center Utrecht, Utrecht, The NetherlandsDepartment of Radiology, University Medical Center Utrecht, Utrecht, The NetherlandsDivision of Heart and Lungs, Departments of Respiratory Medicine and Lung Transplantation, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The NetherlandsDepartment of Pulmonology, St. Antonius Hospital Nieuwegein, Koekoekslaan 1, 3435CM Nieuwegein, The NetherlandsDepartment of Pulmonology, St. Antonius Hospital Nieuwegein, Koekoekslaan 1, 3435CM Nieuwegein, The NetherlandsDivision of Heart and Lungs, Departments of Respiratory Medicine and Lung Transplantation, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The NetherlandsScedosporium/Pseudallescheria species are frequently seen in cystic fibrosis patients. However, disseminated forms after lung transplantation in these patients are rarely seen, but often with poor outcome. In this case report we describe a lung transplant recipient with cystic fibrosis who developed a spondylodiscitis that was caused by Scedosporium apiospermum. The patient was treated with anti-fungal treatment by voriconazole for over three years with a clinical good response and without the need for surgical intervention. To our opinion this is the first anti-fungal treated case of invasive disease caused by Scedosporium/Pseudallescheria in a cystic fibrosis (CF) patient who underwent lung transplantation that survived.http://dx.doi.org/10.1155/2011/460313 |
| spellingShingle | B. Luijk M. B. Ekkelenkamp P. A. De Jong J. M. Kwakkel-van Erp J. C. Grutters D. A. van Kessel E. A. van de Graaf Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum Case Reports in Infectious Diseases |
| title | Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum |
| title_full | Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum |
| title_fullStr | Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum |
| title_full_unstemmed | Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum |
| title_short | Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum |
| title_sort | effective prolonged therapy with voriconazole in a lung transplant recipient with spondylodiscitis induced by scedosporium apiospermum |
| url | http://dx.doi.org/10.1155/2011/460313 |
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