Uncovering the Anti-Herpetic Activity of Anionic Peptides Derived From the Cytoplasmic Domain of Nectin-1

Uncovering the Anti-Herpetic Activity of Anionic Peptides Derived From the Cytoplasmic Domain of Nectin-1

Nectin-1/herpes simplex virus glycoprotein D (HSV gD) interaction is crucial to drive herpes simplex virus (HSV) entry. Polyanions are known to show great potential as antivirals. Thus, we explored a peptide-based biotherapeutic approach and, for the first time, evaluated an anionic peptide derived...

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Main Authors: Rakesh Rahangdale, Sumit Birangal, Gautham Shenoy, Fayaz Shaik Mohammad, Mukesh Pasupuleti, Raghu Chandrashekar Hariharapura
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.1177/11779322251344130
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