A Novel Polyherbal Formulation Modulates Cyclophosphamide-Induced Cytotoxicity in TM3 Leydig Cells and Delays Fictive Ejaculation in Spinal Cord Transected Male Rats

A Novel Polyherbal Formulation Modulates Cyclophosphamide-Induced Cytotoxicity in TM3 Leydig Cells and Delays Fictive Ejaculation in Spinal Cord Transected Male Rats

<b>Background</b>: Cyclophosphamide (CP) chemotherapy is commonly associated with various side effects. The development of an effective therapy capable of counteracting these effects is of great interest. <b>Objectives</b>: We evaluated the effects of a novel polyherbal formu...

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Bibliographic Details
Main Authors: Patrick Brice Defo Deeh, Hye-Yong Kim, Kiseok Han, Anbazhagan Sathiyaseelan, Hyun-Jong Cho, Myeong-Hyeon Wang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceuticals
Subjects:
cyclophosphamide
polyherbal formulation
TRPV1
TRPM2
TM3 Leydig cells
fictive ejaculation
Online Access:https://www.mdpi.com/1424-8247/18/6/803
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