Significant association between three atherosclerosis indexes and stroke risk.
<h4>Background</h4>To evaluate the associations of three atherosclerosis indexes with stroke in a population aged 65 years and older.<h4>Methods</h4>A sample was obtained from wave 2011 to wave 2015 of the China Health and Retirement Longitudinal Study. Multivariate logistic...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0315396 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841555477214789632 |
|---|---|
| author | Xin Wang Lili Wu Peng Shu Wei Yu Wangfang Yu |
| author_facet | Xin Wang Lili Wu Peng Shu Wei Yu Wangfang Yu |
| author_sort | Xin Wang |
| collection | DOAJ |
| description | <h4>Background</h4>To evaluate the associations of three atherosclerosis indexes with stroke in a population aged 65 years and older.<h4>Methods</h4>A sample was obtained from wave 2011 to wave 2015 of the China Health and Retirement Longitudinal Study. Multivariate logistic regression models were used to estimate odds ratios (ORs) with 95% confidence intervals (CIs) for stroke in the quartiles of three atherosclerosis indexes, and restricted cubic splines were constructed.<h4>Results</h4>Four hundred and fifty-four of the 21,913 eligible participants had stroke. After multivariate adjustments and with respect to the lowest quartiles, the ORs (95% CIs) of stroke in the highest quartiles of the atherogenic index of plasma (AIP), the Castelli risk index I (CRI-I), and the Castelli risk index II (CRI-II) were 1.35 (0.99-1.83), 1.52 (1.13-2.06), and 1.40 (1.05-1.86), respectively. When assessed as a continuous exposure, per-unit increases in the AIP, CRI-I, and CRI-II were independently associated with a 49% (OR: 1.49, 95% CI: 1.07-2.08), 6% (OR: 1.06, 95% CI: 1.02-1.11), and 14% (OR: 1.14, 95% CI: 1.03-1.27) increase in the risk of stroke, respectively.<h4>Conclusion</h4>The three atherosclerosis indexes studied-the AIP, CRI-I, and CRI-II-were found to be predictors of stroke in a Chinese population. |
| format | Article |
| id | doaj-art-a165245da9644e008d4ada9dc9a664ae |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-a165245da9644e008d4ada9dc9a664ae2025-01-08T05:32:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-011912e031539610.1371/journal.pone.0315396Significant association between three atherosclerosis indexes and stroke risk.Xin WangLili WuPeng ShuWei YuWangfang Yu<h4>Background</h4>To evaluate the associations of three atherosclerosis indexes with stroke in a population aged 65 years and older.<h4>Methods</h4>A sample was obtained from wave 2011 to wave 2015 of the China Health and Retirement Longitudinal Study. Multivariate logistic regression models were used to estimate odds ratios (ORs) with 95% confidence intervals (CIs) for stroke in the quartiles of three atherosclerosis indexes, and restricted cubic splines were constructed.<h4>Results</h4>Four hundred and fifty-four of the 21,913 eligible participants had stroke. After multivariate adjustments and with respect to the lowest quartiles, the ORs (95% CIs) of stroke in the highest quartiles of the atherogenic index of plasma (AIP), the Castelli risk index I (CRI-I), and the Castelli risk index II (CRI-II) were 1.35 (0.99-1.83), 1.52 (1.13-2.06), and 1.40 (1.05-1.86), respectively. When assessed as a continuous exposure, per-unit increases in the AIP, CRI-I, and CRI-II were independently associated with a 49% (OR: 1.49, 95% CI: 1.07-2.08), 6% (OR: 1.06, 95% CI: 1.02-1.11), and 14% (OR: 1.14, 95% CI: 1.03-1.27) increase in the risk of stroke, respectively.<h4>Conclusion</h4>The three atherosclerosis indexes studied-the AIP, CRI-I, and CRI-II-were found to be predictors of stroke in a Chinese population.https://doi.org/10.1371/journal.pone.0315396 |
| spellingShingle | Xin Wang Lili Wu Peng Shu Wei Yu Wangfang Yu Significant association between three atherosclerosis indexes and stroke risk. PLoS ONE |
| title | Significant association between three atherosclerosis indexes and stroke risk. |
| title_full | Significant association between three atherosclerosis indexes and stroke risk. |
| title_fullStr | Significant association between three atherosclerosis indexes and stroke risk. |
| title_full_unstemmed | Significant association between three atherosclerosis indexes and stroke risk. |
| title_short | Significant association between three atherosclerosis indexes and stroke risk. |
| title_sort | significant association between three atherosclerosis indexes and stroke risk |
| url | https://doi.org/10.1371/journal.pone.0315396 |
| work_keys_str_mv | AT xinwang significantassociationbetweenthreeatherosclerosisindexesandstrokerisk AT liliwu significantassociationbetweenthreeatherosclerosisindexesandstrokerisk AT pengshu significantassociationbetweenthreeatherosclerosisindexesandstrokerisk AT weiyu significantassociationbetweenthreeatherosclerosisindexesandstrokerisk AT wangfangyu significantassociationbetweenthreeatherosclerosisindexesandstrokerisk |