Decoding the immune microenvironment of secondary chronic myelomonocytic leukemia due to diffuse large B-cell lymphoma with CD19 CAR-T failure by single-cell RNA-sequencing

Decoding the immune microenvironment of secondary chronic myelomonocytic leukemia due to diffuse large B-cell lymphoma with CD19 CAR-T failure by single-cell RNA-sequencing

Abstract. Background:. Several studies have demonstrated the occurrence of secondary tumors as a rare but significant complication of chimeric antigen receptor T (CAR-T) cell therapy, underscoring the need for a detailed investigation. Given the limited variety of secondary tumor types reported to...

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Main Authors: Xudong Li, Hong Huang, Fang Wang, Mengjia Li, Binglei Zhang, Jianxiang Shi, Yuke Liu, Mengya Gao, Mingxia Sun, Haixia Cao, Danfeng Zhang, Na Shen, Weijie Cao, Zhilei Bian, Haizhou Xing, Wei Li, Linping Xu, Shiyu Zuo, Yongping Song, Tingting Yang, Xiuyuan Hao
Format: Article
Language:English
Published: Wolters Kluwer 2025-08-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000003690
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