Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end filling

Aim: To evaluate the influence of blood contamination on the bond strength and apatite forming ability of Biodentine used as root-end filling material. Methodology: Eighty (n = 80) extracted single-rooted, sound human maxillary anterior teeth were prepared and obturated. Then, the roots were resecte...

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Main Authors: M. Shalabi, S. Saber, T. Elsewify
Format: Article
Language:English
Published: Springer 2020-12-01
Series:Saudi Dental Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S1013905219309666
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author M. Shalabi
S. Saber
T. Elsewify
author_facet M. Shalabi
S. Saber
T. Elsewify
author_sort M. Shalabi
collection DOAJ
description Aim: To evaluate the influence of blood contamination on the bond strength and apatite forming ability of Biodentine used as root-end filling material. Methodology: Eighty (n = 80) extracted single-rooted, sound human maxillary anterior teeth were prepared and obturated. Then, the roots were resected, retrograde cavities were prepared and Biodentine was inserted as the root-end filling material. Teeth were then randomly divided into 2 equal groups (n = 40) according to the setting environment of Biodentine i.e., group A where setting took place in human blood and group B where setting took place in deionized water (control group). Teeth were incubated at 37  °C for 45 min to ensure complete setting. Root discs with the filling material in their core were prepared. Push-out bond strength test was performed using a universal testing machine and failure mode was examined. Both groups were aged in HBSS for 30 days. Apatite nucleation was evaluated at one-day, 7-days, and 30-days interval using SEM for morphological analysis and EDX for elemental analysis. Calculation of the Ca/P ratios was performed in addition to XRD for crystal phase analysis. Results: Blood contamination (group A) resulted in significant reduction of bond strength values. It also affected the amount of apatite deposition on the material surface and interfacial spaces with higher Ca/P ratios than that of the normal stoichiometric hydroxyapatite. Conclusions: Blood contamination during setting of Biodentine had a detrimental effect on the bond strength and reduced the nucleation of apatite in comparison to non-contaminated group.
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spelling doaj-art-a14643721afd4e009afe3a1e455321c82025-08-20T02:56:47ZengSpringerSaudi Dental Journal1013-90522020-12-0132837338110.1016/j.sdentj.2019.11.005Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end fillingM. Shalabi0S. Saber1T. Elsewify2Department of Endodontics, Ain Shams University, Cairo, EgyptDepartment of Endodontics, Ain Shams University, Cairo, Egypt; Department of Endodontics, The British University, Cairo, EgyptDepartment of Endodontics, Ain Shams University, Cairo, Egypt; Corresponding author at: Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.Aim: To evaluate the influence of blood contamination on the bond strength and apatite forming ability of Biodentine used as root-end filling material. Methodology: Eighty (n = 80) extracted single-rooted, sound human maxillary anterior teeth were prepared and obturated. Then, the roots were resected, retrograde cavities were prepared and Biodentine was inserted as the root-end filling material. Teeth were then randomly divided into 2 equal groups (n = 40) according to the setting environment of Biodentine i.e., group A where setting took place in human blood and group B where setting took place in deionized water (control group). Teeth were incubated at 37  °C for 45 min to ensure complete setting. Root discs with the filling material in their core were prepared. Push-out bond strength test was performed using a universal testing machine and failure mode was examined. Both groups were aged in HBSS for 30 days. Apatite nucleation was evaluated at one-day, 7-days, and 30-days interval using SEM for morphological analysis and EDX for elemental analysis. Calculation of the Ca/P ratios was performed in addition to XRD for crystal phase analysis. Results: Blood contamination (group A) resulted in significant reduction of bond strength values. It also affected the amount of apatite deposition on the material surface and interfacial spaces with higher Ca/P ratios than that of the normal stoichiometric hydroxyapatite. Conclusions: Blood contamination during setting of Biodentine had a detrimental effect on the bond strength and reduced the nucleation of apatite in comparison to non-contaminated group.http://www.sciencedirect.com/science/article/pii/S1013905219309666Apatite forming abilityBiodentineBiointeractivityBlood contaminationBond strengthRoot-end filling
spellingShingle M. Shalabi
S. Saber
T. Elsewify
Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end filling
Saudi Dental Journal
Apatite forming ability
Biodentine
Biointeractivity
Blood contamination
Bond strength
Root-end filling
title Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end filling
title_full Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end filling
title_fullStr Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end filling
title_full_unstemmed Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end filling
title_short Influence of blood contamination on the bond strength and biointeractivity of Biodentine used as root-end filling
title_sort influence of blood contamination on the bond strength and biointeractivity of biodentine used as root end filling
topic Apatite forming ability
Biodentine
Biointeractivity
Blood contamination
Bond strength
Root-end filling
url http://www.sciencedirect.com/science/article/pii/S1013905219309666
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AT telsewify influenceofbloodcontaminationonthebondstrengthandbiointeractivityofbiodentineusedasrootendfilling