The effect of physical exercise on apathy in older adults: a systematic review and meta-analysis

ObjectivesThe objectives of this systematic review and meta-analysis were to evaluate the overall efficacy of physical exercise on apathy in older adults and to provide evidence for alleviating and improving apathy.MethodsThis study was conducted following the PRISMA guidelines and the Cochrane Hand...

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Main Authors: Haichang Jia, Zhengyang Mei, Yang Luo, Xintong Mou, Jing Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1617272/full
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author Haichang Jia
Zhengyang Mei
Yang Luo
Xintong Mou
Jing Huang
author_facet Haichang Jia
Zhengyang Mei
Yang Luo
Xintong Mou
Jing Huang
author_sort Haichang Jia
collection DOAJ
description ObjectivesThe objectives of this systematic review and meta-analysis were to evaluate the overall efficacy of physical exercise on apathy in older adults and to provide evidence for alleviating and improving apathy.MethodsThis study was conducted following the PRISMA guidelines and the Cochrane Handbook for the Evaluation of Systems of Intervention. A comprehensive search was performed across databases, including Cochrane, EMBASE, PubMed, and Web of Science, with a cutoff date of January 2025. Data extraction, organization, and quality assessment were performed using appropriate software. Stata was used to analyze and process the data and test for publication bias.ResultsThe analysis included 9 RCTs involving a total of 356 participants. The meta-analysis revealed a significant improvement in apathy (SMD = −0.32; 95% CI −0.53 to −0.11; p < 0.01) after the physical exercise intervention.ConclusionPhysical exercise effectively alleviates and improves apathy in older adults. Physical exercise is characterized by low risk and high therapeutic benefits and can be used as an alternative or adjunct to medications for the treatment of apathy. Given its favorable safety and efficacy profile, physical exercise should be an important intervention in the treatment of apathy in older adults, while control of the intensity of exercise and supervision of the safety of the exercise process must be considered.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/view/CRD420251123484, CRD420251123484.
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spelling doaj-art-a140a9dd0af54b41bfa818161ebebab72025-08-21T04:10:30ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-08-011310.3389/fpubh.2025.16172721617272The effect of physical exercise on apathy in older adults: a systematic review and meta-analysisHaichang JiaZhengyang MeiYang LuoXintong MouJing HuangObjectivesThe objectives of this systematic review and meta-analysis were to evaluate the overall efficacy of physical exercise on apathy in older adults and to provide evidence for alleviating and improving apathy.MethodsThis study was conducted following the PRISMA guidelines and the Cochrane Handbook for the Evaluation of Systems of Intervention. A comprehensive search was performed across databases, including Cochrane, EMBASE, PubMed, and Web of Science, with a cutoff date of January 2025. Data extraction, organization, and quality assessment were performed using appropriate software. Stata was used to analyze and process the data and test for publication bias.ResultsThe analysis included 9 RCTs involving a total of 356 participants. The meta-analysis revealed a significant improvement in apathy (SMD = −0.32; 95% CI −0.53 to −0.11; p < 0.01) after the physical exercise intervention.ConclusionPhysical exercise effectively alleviates and improves apathy in older adults. Physical exercise is characterized by low risk and high therapeutic benefits and can be used as an alternative or adjunct to medications for the treatment of apathy. Given its favorable safety and efficacy profile, physical exercise should be an important intervention in the treatment of apathy in older adults, while control of the intensity of exercise and supervision of the safety of the exercise process must be considered.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/view/CRD420251123484, CRD420251123484.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1617272/fullphysical exerciseapathyolder adultsnon-pharmacological interventionsystematic reviewmeta-analysis
spellingShingle Haichang Jia
Zhengyang Mei
Yang Luo
Xintong Mou
Jing Huang
The effect of physical exercise on apathy in older adults: a systematic review and meta-analysis
Frontiers in Public Health
physical exercise
apathy
older adults
non-pharmacological intervention
systematic review
meta-analysis
title The effect of physical exercise on apathy in older adults: a systematic review and meta-analysis
title_full The effect of physical exercise on apathy in older adults: a systematic review and meta-analysis
title_fullStr The effect of physical exercise on apathy in older adults: a systematic review and meta-analysis
title_full_unstemmed The effect of physical exercise on apathy in older adults: a systematic review and meta-analysis
title_short The effect of physical exercise on apathy in older adults: a systematic review and meta-analysis
title_sort effect of physical exercise on apathy in older adults a systematic review and meta analysis
topic physical exercise
apathy
older adults
non-pharmacological intervention
systematic review
meta-analysis
url https://www.frontiersin.org/articles/10.3389/fpubh.2025.1617272/full
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