Pro-inflammatory effects of endogenous and recombinant MDA-7/IL-24 with RGD peptide on human hepatic stellate cells

Pro-inflammatory effects of endogenous and recombinant MDA-7/IL-24 with RGD peptide on human hepatic stellate cells

Abstract Hepatic stellate cells (HSCs) serve as pivotal mediators of liver fibrogenesis. This study investigates the pro-inflammatory effects of melanoma differentiation-associated gene-7/interleukin-24 (MDA-7/IL-24) within both murine and cellular models. By employing the hydrodynamic injection of...

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Bibliographic Details
Main Authors: Afrooz Daneshparvar, Seyed Younes Hosseini, Nasrin Hamidizadeh, Mohabbat Jamhiri, Nader Tanideh, Maryam Sadat Sadati, Iman Jamhiri
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Human hepatic stellate cells
LX-2
MDA-7/IL-24
RGD peptide
Inflammation
Online Access:https://doi.org/10.1038/s41598-025-06850-9
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