Opportunities of<sup>13</sup>C NMR spectroscopy of high resolution for metabolomic analysis of oral liquid
NMR-spectroscopy has a growing importance in medicine as a tool for metabolic screening for abnormalities in biological fluids. Carbon is the basis of the most biologically significant molecules and13C NMR spectroscopy involves the direct measurement of these compounds. Clinical examination of patie...
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| Format: | Article |
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| Language: | Russian |
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LLC "Endo Press"
2020-04-01
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| Series: | Эндодонтия Today |
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| Online Access: | https://www.endodont.ru/jour/article/view/262 |
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| description | NMR-spectroscopy has a growing importance in medicine as a tool for metabolic screening for abnormalities in biological fluids. Carbon is the basis of the most biologically significant molecules and13C NMR spectroscopy involves the direct measurement of these compounds. Clinical examination of patients, men and women, aged from 18 to 30 years, was carried out. Particular attention was paid to the detection of wedge-shaped defects of teeth hard tissues at various stages of this disease, as well as co-factors of its occurrence. NMR spectroscopy of carbon isotope13С nuclei of oral liquid samples from a healthy person (control) and patients with severe wedge-shaped lesions was chosen as a laboratory testing method. Studies have shown the analytical capabilities of oral liquid13C NMR spectroscopy of high resolution and promising directions for finding markers of dental diseases in their early stages. |
| format | Article |
| id | doaj-art-a13200ac5a634129b4ac3e552be1e4f8 |
| institution | Kabale University |
| issn | 1683-2981 1726-7242 |
| language | Russian |
| publishDate | 2020-04-01 |
| publisher | LLC "Endo Press" |
| record_format | Article |
| series | Эндодонтия Today |
| spelling | doaj-art-a13200ac5a634129b4ac3e552be1e4f82025-08-20T03:59:04ZrusLLC "Endo Press"Эндодонтия Today1683-29811726-72422020-04-011441215249Opportunities of<sup>13</sup>C NMR spectroscopy of high resolution for metabolomic analysis of oral liquid0123ФГБОУ ВО МГМСУ им. А.И. ЕвдокимоваФГБОУ ВО МГМСУ им. А.И. ЕвдокимоваФГБОУ ВО МГМСУ им. А.И. ЕвдокимоваФГБУН ИОНХ им. Н.С. Курнакова РАНNMR-spectroscopy has a growing importance in medicine as a tool for metabolic screening for abnormalities in biological fluids. Carbon is the basis of the most biologically significant molecules and13C NMR spectroscopy involves the direct measurement of these compounds. Clinical examination of patients, men and women, aged from 18 to 30 years, was carried out. Particular attention was paid to the detection of wedge-shaped defects of teeth hard tissues at various stages of this disease, as well as co-factors of its occurrence. NMR spectroscopy of carbon isotope13С nuclei of oral liquid samples from a healthy person (control) and patients with severe wedge-shaped lesions was chosen as a laboratory testing method. Studies have shown the analytical capabilities of oral liquid13C NMR spectroscopy of high resolution and promising directions for finding markers of dental diseases in their early stages.https://www.endodont.ru/jour/article/view/262клиновидные дефектыметаболомикамолодые пациентыротовая жидкостьямр-спектроскопияmetabolomicsnmr spectroscopyoral liquidwedge-shaped lesionsyoung patients |
| spellingShingle | Opportunities of<sup>13</sup>C NMR spectroscopy of high resolution for metabolomic analysis of oral liquid Эндодонтия Today клиновидные дефекты метаболомика молодые пациенты ротовая жидкость ямр-спектроскопия metabolomics nmr spectroscopy oral liquid wedge-shaped lesions young patients |
| title | Opportunities of<sup>13</sup>C NMR spectroscopy of high resolution for metabolomic analysis of oral liquid |
| title_full | Opportunities of<sup>13</sup>C NMR spectroscopy of high resolution for metabolomic analysis of oral liquid |
| title_fullStr | Opportunities of<sup>13</sup>C NMR spectroscopy of high resolution for metabolomic analysis of oral liquid |
| title_full_unstemmed | Opportunities of<sup>13</sup>C NMR spectroscopy of high resolution for metabolomic analysis of oral liquid |
| title_short | Opportunities of<sup>13</sup>C NMR spectroscopy of high resolution for metabolomic analysis of oral liquid |
| title_sort | opportunities of sup 13 sup c nmr spectroscopy of high resolution for metabolomic analysis of oral liquid |
| topic | клиновидные дефекты метаболомика молодые пациенты ротовая жидкость ямр-спектроскопия metabolomics nmr spectroscopy oral liquid wedge-shaped lesions young patients |
| url | https://www.endodont.ru/jour/article/view/262 |