Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological Study
Background. Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. Extensive studies on Iranian MF patients are absent. The present study aimed to produce updated clinical information on Iranian MF patients. Methods. This was a retrospective, descriptive, single-center study...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Skin Cancer |
| Online Access: | http://dx.doi.org/10.1155/2015/306543 |
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| author | Farahnaz Fatemi Naeini Bahareh Abtahi-Naeini Hamidreza Sadeghiyan Mohammad Ali Nilforoushzadeh Jamshid Najafian Mohsen Pourazizi |
| author_facet | Farahnaz Fatemi Naeini Bahareh Abtahi-Naeini Hamidreza Sadeghiyan Mohammad Ali Nilforoushzadeh Jamshid Najafian Mohsen Pourazizi |
| author_sort | Farahnaz Fatemi Naeini |
| collection | DOAJ |
| description | Background. Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. Extensive studies on Iranian MF patients are absent. The present study aimed to produce updated clinical information on Iranian MF patients. Methods. This was a retrospective, descriptive, single-center study, including all cases of MF seen in the Department of Dermatology, University Hospital of Isfahan, Iran, between 2003 and 2013. Data systematically recorded for each patient included clinical, biological, histological, and molecular findings. Results. Eighty-six patients with clinical and histologic diagnosis of MF were included in the study. Thirty-nine patients (45.3%) were male. Female predominance was observed in patients (male : female ratio is 1 : 1.2). Patients were between 7 and 84 years of age (median: 41). The interval from disease onset to diagnosis ranged from 0 to 55 years (median: 1 year). Eighteen cases (20.9%) had unusual variants of MF. The most common types included hypopigmented and poikilodermatous MF. Childhood cases of MF constituted 5.8% (5/86) of all patients. The early stages were seen in 82 cases (95.34%). Conclusion. The major differences in epidemiologic characteristics of MF in Iran are the lack of male predominance and the lower age of patients at the time of diagnosis. |
| format | Article |
| id | doaj-art-a13171d4678945e6b87d5e7ed1b030b3 |
| institution | OA Journals |
| issn | 2090-2905 2090-2913 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Skin Cancer |
| spelling | doaj-art-a13171d4678945e6b87d5e7ed1b030b32025-08-20T02:20:09ZengWileyJournal of Skin Cancer2090-29052090-29132015-01-01201510.1155/2015/306543306543Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological StudyFarahnaz Fatemi Naeini0Bahareh Abtahi-Naeini1Hamidreza Sadeghiyan2Mohammad Ali Nilforoushzadeh3Jamshid Najafian4Mohsen Pourazizi5Skin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, IranSkin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, IranStudents’ Research Committee, Isfahan University of Medical Sciences, Isfahan, IranSkin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranCardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranStudents’ Research Committee, Semnan University of Medical Sciences, Semnan, IranBackground. Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. Extensive studies on Iranian MF patients are absent. The present study aimed to produce updated clinical information on Iranian MF patients. Methods. This was a retrospective, descriptive, single-center study, including all cases of MF seen in the Department of Dermatology, University Hospital of Isfahan, Iran, between 2003 and 2013. Data systematically recorded for each patient included clinical, biological, histological, and molecular findings. Results. Eighty-six patients with clinical and histologic diagnosis of MF were included in the study. Thirty-nine patients (45.3%) were male. Female predominance was observed in patients (male : female ratio is 1 : 1.2). Patients were between 7 and 84 years of age (median: 41). The interval from disease onset to diagnosis ranged from 0 to 55 years (median: 1 year). Eighteen cases (20.9%) had unusual variants of MF. The most common types included hypopigmented and poikilodermatous MF. Childhood cases of MF constituted 5.8% (5/86) of all patients. The early stages were seen in 82 cases (95.34%). Conclusion. The major differences in epidemiologic characteristics of MF in Iran are the lack of male predominance and the lower age of patients at the time of diagnosis.http://dx.doi.org/10.1155/2015/306543 |
| spellingShingle | Farahnaz Fatemi Naeini Bahareh Abtahi-Naeini Hamidreza Sadeghiyan Mohammad Ali Nilforoushzadeh Jamshid Najafian Mohsen Pourazizi Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological Study Journal of Skin Cancer |
| title | Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological Study |
| title_full | Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological Study |
| title_fullStr | Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological Study |
| title_full_unstemmed | Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological Study |
| title_short | Mycosis Fungoides in Iranian Population: An Epidemiological and Clinicopathological Study |
| title_sort | mycosis fungoides in iranian population an epidemiological and clinicopathological study |
| url | http://dx.doi.org/10.1155/2015/306543 |
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