Gene deletion as a possible strategy adopted by New World Leishmania infantum to maximize geographic dispersion.

Gene deletion as a possible strategy adopted by New World Leishmania infantum to maximize geographic dispersion.

<h4>Background</h4>The present study investigates implications of a sub-chromosomal deletion in Leishmania infantum strains, the causative agent of American Visceral Leishmaniasis (AVL). Primarily found in New World strains, the deletion leads to the absence of the ecto-3'-nucleotid...

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Main Authors: Monique Florêncio, Marne Coimbra Batalha Chagas, Anderson Guimarães-Costa, Jullyanna Oliveira, Ingrid Waclawiak, Thamara K F Oliveira, Elvira Maria Saraiva, Anita Leocadio Freitas-Mesquita, José Roberto Meyer-Fernandes, Laura Aragão-Farias, Camilly Enes Trindade, Patricia Cuervo, Renata Azevedo do Nascimento, Otacilio C Moreira, Flávia Lima Ribeiro-Gomes, Yara M Traub-Csekö, Erich Loza Telleria, Slavica Vaselek, Tereza Leštinová, Petr Volf, Gerald F Späth, Elisa Cupolillo, Mariana Côrtes Boité
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012938
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