Three New Triterpene Glycosides from the Roots of <i>Deutzia</i> x <i>Hybrida</i> “Strawberry Fields” (Hydrangeaceae)
Three new triterpene glycosides were isolated from <i>Deutzia</i> x <i>hybrida</i> “Strawberry Fields” cultivar via aqueous–ethanolic extraction of the roots, including one derivative of sumaresinolic acid and two of echinocystic acid: 3-<i>O</i>-β-D-glucuronopyra...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/29/23/5781 |
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| Summary: | Three new triterpene glycosides were isolated from <i>Deutzia</i> x <i>hybrida</i> “Strawberry Fields” cultivar via aqueous–ethanolic extraction of the roots, including one derivative of sumaresinolic acid and two of echinocystic acid: 3-<i>O</i>-β-D-glucuronopyranosylsumaresinolic acid 28-<i>O</i>-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl ester, 3-<i>O</i>-β-D-glucuronopyranosylechinocystic acid 28-<i>O</i>-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl ester, and 3-<i>O</i>-α-L-arabinopyranosyl-(1→3)-β-D-glucuronopyranosylechinocystic acid 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl ester. As none of the isolated saponins were previously documented in the literature, their structural elucidation required extensive 1D and homo- and heteronuclear 2D NMR spectroscopy, as well as mass spectrometry analysis. All three glycosides were tested for their stimulatory activity of the sweet taste receptor TAS1R2/TAS1R3. It is the first chemical and biological investigation of <i>Deutzia</i> x <i>hybrida</i> “Strawberry Fields” as well as the first report of sumaresinolic acid glycosides in <i>Deutzia</i> genus. |
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| ISSN: | 1420-3049 |