Imitators of severe preeclampsia: on differential diagnosis and multidisciplinary management
Preeclampsia (PE) is not only a disease of pregnant women, but also a disease with lifelong consequences for mother and child. Making an early diagnosis and differential diagnosis of PE is crucial yet challenging, since PE can be mistaken for other internal diseases or surgical conditions. Despite t...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2019-05-01
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| Series: | Акушерство, гинекология и репродукция |
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| Online Access: | https://www.gynecology.su/jour/article/view/555 |
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| author | A. N. Strizhakov I. V. Ignatko E. V. Timokhina |
| author_facet | A. N. Strizhakov I. V. Ignatko E. V. Timokhina |
| author_sort | A. N. Strizhakov |
| collection | DOAJ |
| description | Preeclampsia (PE) is not only a disease of pregnant women, but also a disease with lifelong consequences for mother and child. Making an early diagnosis and differential diagnosis of PE is crucial yet challenging, since PE can be mistaken for other internal diseases or surgical conditions. Despite the variety of clinical symptoms of thrombotic microangiopathy that may manifest in a non-typical picture of PE, progressive multiple organ failure develops in all cases. It seems promising to study the role of matrix metalloproteinases and determine the genetic predisposition to early and severe PE. The forecast and prevention attempts must begin from the fertile cycle. A better knowledge of biochemical and genetic markers along with the clinical and instrumental tests will reduce the morbidity and mortality in PE patients. |
| format | Article |
| id | doaj-art-a1097b95bd874501a0d723a842ea470c |
| institution | DOAJ |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| publishDate | 2019-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj-art-a1097b95bd874501a0d723a842ea470c2025-08-20T03:19:14ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942019-05-01131707810.17749/2313-7347.2019.13.1.070-078494Imitators of severe preeclampsia: on differential diagnosis and multidisciplinary managementA. N. Strizhakov0I. V. Ignatko1E. V. Timokhina2I.M. Sechenov First Moscow State Medical University, Health Ministry of Russian FederationI.M. Sechenov First Moscow State Medical University, Health Ministry of Russian FederationI.M. Sechenov First Moscow State Medical University, Health Ministry of Russian FederationPreeclampsia (PE) is not only a disease of pregnant women, but also a disease with lifelong consequences for mother and child. Making an early diagnosis and differential diagnosis of PE is crucial yet challenging, since PE can be mistaken for other internal diseases or surgical conditions. Despite the variety of clinical symptoms of thrombotic microangiopathy that may manifest in a non-typical picture of PE, progressive multiple organ failure develops in all cases. It seems promising to study the role of matrix metalloproteinases and determine the genetic predisposition to early and severe PE. The forecast and prevention attempts must begin from the fertile cycle. A better knowledge of biochemical and genetic markers along with the clinical and instrumental tests will reduce the morbidity and mortality in PE patients.https://www.gynecology.su/jour/article/view/555preeclampsiathrombotic microangiopathymultiple organ failurematrix metalloproteinases |
| spellingShingle | A. N. Strizhakov I. V. Ignatko E. V. Timokhina Imitators of severe preeclampsia: on differential diagnosis and multidisciplinary management Акушерство, гинекология и репродукция preeclampsia thrombotic microangiopathy multiple organ failure matrix metalloproteinases |
| title | Imitators of severe preeclampsia: on differential diagnosis and multidisciplinary management |
| title_full | Imitators of severe preeclampsia: on differential diagnosis and multidisciplinary management |
| title_fullStr | Imitators of severe preeclampsia: on differential diagnosis and multidisciplinary management |
| title_full_unstemmed | Imitators of severe preeclampsia: on differential diagnosis and multidisciplinary management |
| title_short | Imitators of severe preeclampsia: on differential diagnosis and multidisciplinary management |
| title_sort | imitators of severe preeclampsia on differential diagnosis and multidisciplinary management |
| topic | preeclampsia thrombotic microangiopathy multiple organ failure matrix metalloproteinases |
| url | https://www.gynecology.su/jour/article/view/555 |
| work_keys_str_mv | AT anstrizhakov imitatorsofseverepreeclampsiaondifferentialdiagnosisandmultidisciplinarymanagement AT ivignatko imitatorsofseverepreeclampsiaondifferentialdiagnosisandmultidisciplinarymanagement AT evtimokhina imitatorsofseverepreeclampsiaondifferentialdiagnosisandmultidisciplinarymanagement |