EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY.
Background Caffeine is a central nervous system stimulant with bronchodilatory effects that may influence pulmonary function. This randomized controlled study aimed to evaluate the effect of caffeine intake and its duration of action on pulmonary function tests (PFTs) in healthy adults. Materi...
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Student's Journal of Health Research
2025-06-01
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| Series: | Student's Journal of Health Research Africa |
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| Online Access: | https://sjhresearchafrica.org/index.php/public-html/article/view/1722/1385 |
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| author | Boyana Krishna Chaitanya M. Srinivasulu Dr. V. Jyothi Vinay Kumar Sayeli |
| author_facet | Boyana Krishna Chaitanya M. Srinivasulu Dr. V. Jyothi Vinay Kumar Sayeli |
| author_sort | Boyana Krishna Chaitanya |
| collection | DOAJ |
| description | Background
Caffeine is a central nervous system stimulant with bronchodilatory effects that may influence pulmonary function. This randomized controlled study aimed to evaluate the effect of caffeine intake and its duration of action on pulmonary function tests (PFTs) in healthy adults.
Materials and Methods
One hundred healthy adults aged 18–35 years were randomly assigned to two groups: caffeine (200 mg oral caffeine, n=50) and control (no intervention, n=50). Pulmonary function parameters—Forced Expiratory Volume in 1 second (FEV₁), Forced Vital Capacity (FVC), FEV₁/FVC ratio, and Peak Expiratory Flow Rate (PEFR)—were measured at baseline and 1, 3, and 6 hours post-intervention.
Results
Participants had a mean age of 25.4 ± 4.8 years, balanced gender distribution (52% male, 48% female), and comparable body mass index (22.5 ± 2.2 kg/m²). The caffeine group showed a significant increase in FEV₁ (3.42 ± 0.39 L to 3.58 ± 0.40 L) and PEFR (7.6 ± 0.9 L/s to 8.1 ± 1.0 L/s) at 1-hour post-intake (p < 0.05). Improvements diminished by 3 hours and returned to baseline by 6 hours. The control group showed no significant changes.
Conclusion
Caffeine intake transiently improves pulmonary function, peaking at 1 hour and subsiding by 6 hours. Abstaining from caffeine for at least 6 hours before PFTs is recommended to avoid confounding results.
Recommendations
Individuals should abstain from caffeine-containing products for at least 6 hours before undergoing pulmonary function testing to ensure accurate and reliable results. |
| format | Article |
| id | doaj-art-a100e91314834a428c1d0ff6124d2c75 |
| institution | Kabale University |
| issn | 2709-9997 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Student's Journal of Health Research |
| record_format | Article |
| series | Student's Journal of Health Research Africa |
| spelling | doaj-art-a100e91314834a428c1d0ff6124d2c752025-08-20T03:40:51ZengStudent's Journal of Health ResearchStudent's Journal of Health Research Africa2709-99972025-06-016618https://doi.org/10.51168/sjhrafrica.v6i6.1722EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY. Boyana Krishna Chaitanya 0M. Srinivasulu 1Dr. V. Jyothi 2Vinay Kumar Sayeli 3Assistant Professor , Department of Physiology , Alluri Sitarama Raju Academy of Medical Sciences, Eluru, Andhra Pradesh, India Associate Professor, Department of Physiology, Government Medical College Eluru, Andhra Pradesh, India Assistant Professor, Department of General Medicine, Siddhartha Medical College, Vijayawada, Andhra Pradesh, India Professor, Department of Pharmacology , Alluri Sitarama Raju academy of medical sciences ,Eluru, Andhra Pradesh, India Background Caffeine is a central nervous system stimulant with bronchodilatory effects that may influence pulmonary function. This randomized controlled study aimed to evaluate the effect of caffeine intake and its duration of action on pulmonary function tests (PFTs) in healthy adults. Materials and Methods One hundred healthy adults aged 18–35 years were randomly assigned to two groups: caffeine (200 mg oral caffeine, n=50) and control (no intervention, n=50). Pulmonary function parameters—Forced Expiratory Volume in 1 second (FEV₁), Forced Vital Capacity (FVC), FEV₁/FVC ratio, and Peak Expiratory Flow Rate (PEFR)—were measured at baseline and 1, 3, and 6 hours post-intervention. Results Participants had a mean age of 25.4 ± 4.8 years, balanced gender distribution (52% male, 48% female), and comparable body mass index (22.5 ± 2.2 kg/m²). The caffeine group showed a significant increase in FEV₁ (3.42 ± 0.39 L to 3.58 ± 0.40 L) and PEFR (7.6 ± 0.9 L/s to 8.1 ± 1.0 L/s) at 1-hour post-intake (p < 0.05). Improvements diminished by 3 hours and returned to baseline by 6 hours. The control group showed no significant changes. Conclusion Caffeine intake transiently improves pulmonary function, peaking at 1 hour and subsiding by 6 hours. Abstaining from caffeine for at least 6 hours before PFTs is recommended to avoid confounding results. Recommendations Individuals should abstain from caffeine-containing products for at least 6 hours before undergoing pulmonary function testing to ensure accurate and reliable results.https://sjhresearchafrica.org/index.php/public-html/article/view/1722/1385caffeinepulmonary function testforced expiratory volume in 1 second (fev₁)peak expiratory flow rate (pefr)bronchodilationrespiratory assessment |
| spellingShingle | Boyana Krishna Chaitanya M. Srinivasulu Dr. V. Jyothi Vinay Kumar Sayeli EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY. Student's Journal of Health Research Africa caffeine pulmonary function test forced expiratory volume in 1 second (fev₁) peak expiratory flow rate (pefr) bronchodilation respiratory assessment |
| title | EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY. |
| title_full | EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY. |
| title_fullStr | EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY. |
| title_full_unstemmed | EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY. |
| title_short | EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY. |
| title_sort | effect of caffeine intake and its duration of action on pulmonary function test a randomized controlled study |
| topic | caffeine pulmonary function test forced expiratory volume in 1 second (fev₁) peak expiratory flow rate (pefr) bronchodilation respiratory assessment |
| url | https://sjhresearchafrica.org/index.php/public-html/article/view/1722/1385 |
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