EFFECT OF CAFFEINE INTAKE AND ITS DURATION OF ACTION ON PULMONARY FUNCTION TEST: A RANDOMIZED CONTROLLED STUDY.
Background Caffeine is a central nervous system stimulant with bronchodilatory effects that may influence pulmonary function. This randomized controlled study aimed to evaluate the effect of caffeine intake and its duration of action on pulmonary function tests (PFTs) in healthy adults. Materi...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Student's Journal of Health Research
2025-06-01
|
| Series: | Student's Journal of Health Research Africa |
| Subjects: | |
| Online Access: | https://sjhresearchafrica.org/index.php/public-html/article/view/1722/1385 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Background
Caffeine is a central nervous system stimulant with bronchodilatory effects that may influence pulmonary function. This randomized controlled study aimed to evaluate the effect of caffeine intake and its duration of action on pulmonary function tests (PFTs) in healthy adults.
Materials and Methods
One hundred healthy adults aged 18–35 years were randomly assigned to two groups: caffeine (200 mg oral caffeine, n=50) and control (no intervention, n=50). Pulmonary function parameters—Forced Expiratory Volume in 1 second (FEV₁), Forced Vital Capacity (FVC), FEV₁/FVC ratio, and Peak Expiratory Flow Rate (PEFR)—were measured at baseline and 1, 3, and 6 hours post-intervention.
Results
Participants had a mean age of 25.4 ± 4.8 years, balanced gender distribution (52% male, 48% female), and comparable body mass index (22.5 ± 2.2 kg/m²). The caffeine group showed a significant increase in FEV₁ (3.42 ± 0.39 L to 3.58 ± 0.40 L) and PEFR (7.6 ± 0.9 L/s to 8.1 ± 1.0 L/s) at 1-hour post-intake (p < 0.05). Improvements diminished by 3 hours and returned to baseline by 6 hours. The control group showed no significant changes.
Conclusion
Caffeine intake transiently improves pulmonary function, peaking at 1 hour and subsiding by 6 hours. Abstaining from caffeine for at least 6 hours before PFTs is recommended to avoid confounding results.
Recommendations
Individuals should abstain from caffeine-containing products for at least 6 hours before undergoing pulmonary function testing to ensure accurate and reliable results. |
|---|---|
| ISSN: | 2709-9997 |