Enhancing PQQ production in Acinetobacter calcoaceticus through uniform design and support vector regression
A novel machine learning-assisted approach for formula optimization, termed UD-SVR, is introduced by combining uniform design with support vector regression. This method was employed to optimize both the formulation and fermentation conditions for pyrroloquinoline quinone (PQQ) production by Acineto...
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| Main Authors: | Yu-han Li, Su-hang Yao, Yan Zhou, Xiu-lan He, Zhe-ming Yuan, Qiu-long Hu, Cheng-wen Shen, Xin Li, Yuan Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1556322/full |
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