Deep tissue photoacoustic imaging with light and sound

Abstract Photoacoustic computed tomography (PACT) can harvest diffusive photons to image the optical absorption contrast of molecules in a scattering medium, with ultrasonically-defined spatial resolution. PACT has been extensively used in preclinical research for imaging functional and molecular in...

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Bibliographic Details
Main Authors: Luca Menozzi, Junjie Yao
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Imaging
Online Access:https://doi.org/10.1038/s44303-024-00048-w
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Summary:Abstract Photoacoustic computed tomography (PACT) can harvest diffusive photons to image the optical absorption contrast of molecules in a scattering medium, with ultrasonically-defined spatial resolution. PACT has been extensively used in preclinical research for imaging functional and molecular information in various animal models, with recent clinical translations. In this review, we aim to highlight the recent technical breakthroughs in PACT and the emerging preclinical and clinical applications in deep tissue imaging.
ISSN:2948-197X