Gallbladder Polyps Are Associated with Proximal Colon Polyps
Background. The association between gallbladder (GB) disease and colorectal precancerous lesions remains elusive. This study sought to explore the association between GB disease and colorectal neoplasms at different locations. Methods. Patients who received general health checkup from January to Dec...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2019/9832482 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849400192746389504 |
|---|---|
| author | Kuan-Chieh Lee Wen-Juei Jeng Chen-Ming Hsu Chia-Jung Kuo Ming-Yao Su Cheng-Tang Chiu |
| author_facet | Kuan-Chieh Lee Wen-Juei Jeng Chen-Ming Hsu Chia-Jung Kuo Ming-Yao Su Cheng-Tang Chiu |
| author_sort | Kuan-Chieh Lee |
| collection | DOAJ |
| description | Background. The association between gallbladder (GB) disease and colorectal precancerous lesions remains elusive. This study sought to explore the association between GB disease and colorectal neoplasms at different locations. Methods. Patients who received general health checkup from January to December 2008 were included and subgrouped into three groups by polyp location: proximal, distal, and whole colon. GB disease and other known risk factors for colon cancer were compared and analyzed. Different types of polyps at different locations were further investigated. Results. Of a total of 3136 patients (1776 men and 1360 women; mean age, 49.3 years) who had colon polyps, 212 (6.8%) had GB stone and 512 (16.3%) had GB polyps. Patients in the proximal colon polyp group had higher rates of GB polyps and stones. GB polyps were independently associated with proximal colon polyps, including both hyperplastic polyps (odds ratio, 1.523; P=0.034) and adenomatous polyps (odds ratio, 1.351; P=0.048). No relationship between GB polyps and distal or any colon polyps was observed. Irrespective of the polyp location (i.e., proximal, distal, or any part of the colon), GB stone did not show any association with colon polyp. Conclusions. We suggested that GB polyps are associated with proximal colon polyps. Colonoscopy may be a more effective strategy for screening proximal precancerous lesions among patients with GB polyps. The association between GB disease and colon polyps demands further prospective investigation. |
| format | Article |
| id | doaj-art-a0d62c49bbc84ed7b731aaa15de29cb7 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-a0d62c49bbc84ed7b731aaa15de29cb72025-08-20T03:38:08ZengWileyGastroenterology Research and Practice1687-61211687-630X2019-01-01201910.1155/2019/98324829832482Gallbladder Polyps Are Associated with Proximal Colon PolypsKuan-Chieh Lee0Wen-Juei Jeng1Chen-Ming Hsu2Chia-Jung Kuo3Ming-Yao Su4Cheng-Tang Chiu5Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital at Linkou, Taoyuan, TaiwanLiver Research Center, Division of Gastroenterology, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan, TaiwanDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital at Linkou, Taoyuan, TaiwanDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital at Linkou, Taoyuan, TaiwanDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital at Linkou, Taoyuan, TaiwanDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital at Linkou, Taoyuan, TaiwanBackground. The association between gallbladder (GB) disease and colorectal precancerous lesions remains elusive. This study sought to explore the association between GB disease and colorectal neoplasms at different locations. Methods. Patients who received general health checkup from January to December 2008 were included and subgrouped into three groups by polyp location: proximal, distal, and whole colon. GB disease and other known risk factors for colon cancer were compared and analyzed. Different types of polyps at different locations were further investigated. Results. Of a total of 3136 patients (1776 men and 1360 women; mean age, 49.3 years) who had colon polyps, 212 (6.8%) had GB stone and 512 (16.3%) had GB polyps. Patients in the proximal colon polyp group had higher rates of GB polyps and stones. GB polyps were independently associated with proximal colon polyps, including both hyperplastic polyps (odds ratio, 1.523; P=0.034) and adenomatous polyps (odds ratio, 1.351; P=0.048). No relationship between GB polyps and distal or any colon polyps was observed. Irrespective of the polyp location (i.e., proximal, distal, or any part of the colon), GB stone did not show any association with colon polyp. Conclusions. We suggested that GB polyps are associated with proximal colon polyps. Colonoscopy may be a more effective strategy for screening proximal precancerous lesions among patients with GB polyps. The association between GB disease and colon polyps demands further prospective investigation.http://dx.doi.org/10.1155/2019/9832482 |
| spellingShingle | Kuan-Chieh Lee Wen-Juei Jeng Chen-Ming Hsu Chia-Jung Kuo Ming-Yao Su Cheng-Tang Chiu Gallbladder Polyps Are Associated with Proximal Colon Polyps Gastroenterology Research and Practice |
| title | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
| title_full | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
| title_fullStr | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
| title_full_unstemmed | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
| title_short | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
| title_sort | gallbladder polyps are associated with proximal colon polyps |
| url | http://dx.doi.org/10.1155/2019/9832482 |
| work_keys_str_mv | AT kuanchiehlee gallbladderpolypsareassociatedwithproximalcolonpolyps AT wenjueijeng gallbladderpolypsareassociatedwithproximalcolonpolyps AT chenminghsu gallbladderpolypsareassociatedwithproximalcolonpolyps AT chiajungkuo gallbladderpolypsareassociatedwithproximalcolonpolyps AT mingyaosu gallbladderpolypsareassociatedwithproximalcolonpolyps AT chengtangchiu gallbladderpolypsareassociatedwithproximalcolonpolyps |