Macrocyclic Azopyrrole: Synthesis, Structure and Fluoride Recognition

A macrocyclic receptor based on azopyrrole and polyether was synthesized, and its structure was characterized by NMR (<sup>1</sup>H and <sup>13</sup>C), HRMS and X-ray crystallography. In the solid state, the macrocyclic molecules could bind methanol through a pair of N-H…O h...

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Main Authors: Ying An, Ying Sun, Zhenming Yin
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Organics
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Online Access:https://www.mdpi.com/2673-401X/6/2/25
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author Ying An
Ying Sun
Zhenming Yin
author_facet Ying An
Ying Sun
Zhenming Yin
author_sort Ying An
collection DOAJ
description A macrocyclic receptor based on azopyrrole and polyether was synthesized, and its structure was characterized by NMR (<sup>1</sup>H and <sup>13</sup>C), HRMS and X-ray crystallography. In the solid state, the macrocyclic molecules could bind methanol through a pair of N-H…O hydrogen bonds and further self-assembled into tubular structures through C-H…N hydrogen bonds. This revealed that the crystal could still keep its porous properties after the included molecules were removed. The UV–Vis titration indicates that the macrocylic receptor can chromogenically and selectively sense fluoride ion in DMSO solution, and the sensing mechanism was rationalized by <sup>1</sup>H NMR.
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id doaj-art-a0d2796d54124fa48fb92c923ace5a5d
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publisher MDPI AG
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spelling doaj-art-a0d2796d54124fa48fb92c923ace5a5d2025-08-20T02:21:49ZengMDPI AGOrganics2673-401X2025-06-01622510.3390/org6020025Macrocyclic Azopyrrole: Synthesis, Structure and Fluoride RecognitionYing An0Ying Sun1Zhenming Yin2Tianjin Key Laboratory of Structure and Performance for Functional Molecule, College of Chemistry, Tianjin Normal University, Tianjin 300387, ChinaTianjin Key Laboratory of Structure and Performance for Functional Molecule, College of Chemistry, Tianjin Normal University, Tianjin 300387, ChinaTianjin Key Laboratory of Structure and Performance for Functional Molecule, College of Chemistry, Tianjin Normal University, Tianjin 300387, ChinaA macrocyclic receptor based on azopyrrole and polyether was synthesized, and its structure was characterized by NMR (<sup>1</sup>H and <sup>13</sup>C), HRMS and X-ray crystallography. In the solid state, the macrocyclic molecules could bind methanol through a pair of N-H…O hydrogen bonds and further self-assembled into tubular structures through C-H…N hydrogen bonds. This revealed that the crystal could still keep its porous properties after the included molecules were removed. The UV–Vis titration indicates that the macrocylic receptor can chromogenically and selectively sense fluoride ion in DMSO solution, and the sensing mechanism was rationalized by <sup>1</sup>H NMR.https://www.mdpi.com/2673-401X/6/2/25macrocyclicazopyrrolesynthesisstructurefluoride detection
spellingShingle Ying An
Ying Sun
Zhenming Yin
Macrocyclic Azopyrrole: Synthesis, Structure and Fluoride Recognition
Organics
macrocyclic
azopyrrole
synthesis
structure
fluoride detection
title Macrocyclic Azopyrrole: Synthesis, Structure and Fluoride Recognition
title_full Macrocyclic Azopyrrole: Synthesis, Structure and Fluoride Recognition
title_fullStr Macrocyclic Azopyrrole: Synthesis, Structure and Fluoride Recognition
title_full_unstemmed Macrocyclic Azopyrrole: Synthesis, Structure and Fluoride Recognition
title_short Macrocyclic Azopyrrole: Synthesis, Structure and Fluoride Recognition
title_sort macrocyclic azopyrrole synthesis structure and fluoride recognition
topic macrocyclic
azopyrrole
synthesis
structure
fluoride detection
url https://www.mdpi.com/2673-401X/6/2/25
work_keys_str_mv AT yingan macrocyclicazopyrrolesynthesisstructureandfluoriderecognition
AT yingsun macrocyclicazopyrrolesynthesisstructureandfluoriderecognition
AT zhenmingyin macrocyclicazopyrrolesynthesisstructureandfluoriderecognition