T model of growth and its application in systems of tumor-immunedynamics

In this paper we introduce a new growth model called Tgrowth model. This model is capable of representing sigmoidal growth as wellas biphasic growth. This dual capability is achieved without introducingadditional parameters. The T model is useful in modeling cellularproliferation or regression of ca...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohammad A. Tabatabai, Wayne M. Eby, Karan P. Singh, Sejong Bae
Format: Article
Language:English
Published: AIMS Press 2013-03-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.925
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832590135959486464
author Mohammad A. Tabatabai
Wayne M. Eby
Karan P. Singh
Sejong Bae
author_facet Mohammad A. Tabatabai
Wayne M. Eby
Karan P. Singh
Sejong Bae
author_sort Mohammad A. Tabatabai
collection DOAJ
description In this paper we introduce a new growth model called Tgrowth model. This model is capable of representing sigmoidal growth as wellas biphasic growth. This dual capability is achieved without introducingadditional parameters. The T model is useful in modeling cellularproliferation or regression of cancer cells, stem cells, bacterial growth anddrug dose-response relationships. We recommend usage of the T growth model forthe growth of tumors as part of any system of differential equations. Use ofthis model within a system will allow more flexibility in representing thenatural rate of tumor growth. For illustration, we examine some systems oftumor-immune interaction in which the T growth rate is applied. We also applythe model to a set of tumor growth data.
format Article
id doaj-art-a0d0578068b84461a58e5bdb23677cc2
institution Kabale University
issn 1551-0018
language English
publishDate 2013-03-01
publisher AIMS Press
record_format Article
series Mathematical Biosciences and Engineering
spelling doaj-art-a0d0578068b84461a58e5bdb23677cc22025-01-24T02:26:12ZengAIMS PressMathematical Biosciences and Engineering1551-00182013-03-0110392593810.3934/mbe.2013.10.925T model of growth and its application in systems of tumor-immunedynamicsMohammad A. Tabatabai0Wayne M. Eby1Karan P. Singh2Sejong Bae3Department of Mathematical Sciences, Cameron University, Lawton, OK 73505Department of Mathematical Sciences, Cameron University, Lawton, OK 73505Department of Mathematical Sciences, Cameron University, Lawton, OK 73505Department of Mathematical Sciences, Cameron University, Lawton, OK 73505In this paper we introduce a new growth model called Tgrowth model. This model is capable of representing sigmoidal growth as wellas biphasic growth. This dual capability is achieved without introducingadditional parameters. The T model is useful in modeling cellularproliferation or regression of cancer cells, stem cells, bacterial growth anddrug dose-response relationships. We recommend usage of the T growth model forthe growth of tumors as part of any system of differential equations. Use ofthis model within a system will allow more flexibility in representing thenatural rate of tumor growth. For illustration, we examine some systems oftumor-immune interaction in which the T growth rate is applied. We also applythe model to a set of tumor growth data.https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.925tumor-immune dynamicsgrowth modelsrnainterference.
spellingShingle Mohammad A. Tabatabai
Wayne M. Eby
Karan P. Singh
Sejong Bae
T model of growth and its application in systems of tumor-immunedynamics
Mathematical Biosciences and Engineering
tumor-immune dynamics
growth models
rnainterference.
title T model of growth and its application in systems of tumor-immunedynamics
title_full T model of growth and its application in systems of tumor-immunedynamics
title_fullStr T model of growth and its application in systems of tumor-immunedynamics
title_full_unstemmed T model of growth and its application in systems of tumor-immunedynamics
title_short T model of growth and its application in systems of tumor-immunedynamics
title_sort t model of growth and its application in systems of tumor immunedynamics
topic tumor-immune dynamics
growth models
rnainterference.
url https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.925
work_keys_str_mv AT mohammadatabatabai tmodelofgrowthanditsapplicationinsystemsoftumorimmunedynamics
AT waynemeby tmodelofgrowthanditsapplicationinsystemsoftumorimmunedynamics
AT karanpsingh tmodelofgrowthanditsapplicationinsystemsoftumorimmunedynamics
AT sejongbae tmodelofgrowthanditsapplicationinsystemsoftumorimmunedynamics