Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives
A series of new oxopyrimidine were prepared by cyclocondensation route with various substituted chalcones in presence of alcoholic solution of potassium hydroxide at reflux temperature. The synthesized oxopyrimidine derivatives were characterized by means of their IR, 1H NMR, mass spectral data and...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2012/258672 |
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| author | Sanjeevan S. Gaikwad Venkat S. Suryawanshi Kishan S. Lohar Dhanaji V. Jadhav Narayan D. Shinde |
| author_facet | Sanjeevan S. Gaikwad Venkat S. Suryawanshi Kishan S. Lohar Dhanaji V. Jadhav Narayan D. Shinde |
| author_sort | Sanjeevan S. Gaikwad |
| collection | DOAJ |
| description | A series of new oxopyrimidine were prepared by cyclocondensation route with various substituted chalcones in presence of alcoholic solution of potassium hydroxide at reflux temperature. The synthesized oxopyrimidine derivatives were characterized by means of their IR, 1H NMR, mass spectral data and elemental analysis. The synthesized oxopyrimidines derivatives were evaluated for antibacterial and antifungal activities, some of them were found to possess significant activity. |
| format | Article |
| id | doaj-art-a0c8575b445445249375a0c913714e08 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-a0c8575b445445249375a0c913714e082025-02-03T05:46:34ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-019117518010.1155/2012/258672Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one DerivativesSanjeevan S. Gaikwad0Venkat S. Suryawanshi1Kishan S. Lohar2Dhanaji V. Jadhav3Narayan D. Shinde4Dept. of Chemistry, Shrikrishna College, Gunjoti, Tal-Omerga, Dist-Osmanabad, Maharashtra-413613, IndiaDept. of Chemistry, PG studies and Research Center, Shri Chattrapati Shivaji College, Omerga, Maharashtra-413 606, IndiaDept. of Chemistry, Shrikrishna College, Gunjoti, Tal-Omerga, Dist-Osmanabad, Maharashtra-413613, IndiaDept. of Chemistry, Y. C. Arts & Science College, Mangrulpir, Dist-Washim, Maharashtra-444 403, IndiaDept. of Chemistry, PG studies and Research Center, Shri Chattrapati Shivaji College, Omerga, Maharashtra-413 606, IndiaA series of new oxopyrimidine were prepared by cyclocondensation route with various substituted chalcones in presence of alcoholic solution of potassium hydroxide at reflux temperature. The synthesized oxopyrimidine derivatives were characterized by means of their IR, 1H NMR, mass spectral data and elemental analysis. The synthesized oxopyrimidines derivatives were evaluated for antibacterial and antifungal activities, some of them were found to possess significant activity.http://dx.doi.org/10.1155/2012/258672 |
| spellingShingle | Sanjeevan S. Gaikwad Venkat S. Suryawanshi Kishan S. Lohar Dhanaji V. Jadhav Narayan D. Shinde Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives E-Journal of Chemistry |
| title | Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives |
| title_full | Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives |
| title_fullStr | Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives |
| title_full_unstemmed | Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives |
| title_short | Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives |
| title_sort | synthesis and biological activity of some 3 4 dihydro 4 4 substituted aryl 6 naptho 2 1 b furan 2 yl pyrimidine 2 1h one derivatives |
| url | http://dx.doi.org/10.1155/2012/258672 |
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