Pseudospherical Bismuth Oxychloride-Modified Carbon Paste Electrode for the Determination of Quinine in Beverages

The extensive use of the alkaloid quinine (QN) in the cosmetic and food industries has induced major concerns relating to its impact on human health, considering its potential toxicity. Therefore, developing sensitive and selective electrochemical sensors is crucial for monitoring QN in environmenta...

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Main Authors: Tijana Mutić, Vesna Stanković, Miloš Ognjanović, Vladimir B. Nikolić, Guanyue Gao, Neso Sojic, Dalibor Stanković
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Electrochem
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Online Access:https://www.mdpi.com/2673-3293/5/4/27
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author Tijana Mutić
Vesna Stanković
Miloš Ognjanović
Vladimir B. Nikolić
Guanyue Gao
Neso Sojic
Dalibor Stanković
author_facet Tijana Mutić
Vesna Stanković
Miloš Ognjanović
Vladimir B. Nikolić
Guanyue Gao
Neso Sojic
Dalibor Stanković
author_sort Tijana Mutić
collection DOAJ
description The extensive use of the alkaloid quinine (QN) in the cosmetic and food industries has induced major concerns relating to its impact on human health, considering its potential toxicity. Therefore, developing sensitive and selective electrochemical sensors is crucial for monitoring QN in environmental, food, and pharmaceutical samples. To respond to this need, a surfactant-supported green synthesis approach, based on a straightforward, organic solvent-free hydrothermal method was employed to synthesize highly crystalline pseudospherical bismuth oxychloride (BiOCl) nanoparticles. This material was used for the enrichment of carbon paste electrodes and its further utilization for the detection and quantification of quinine. They have superior electrocatalytic performance, due to their size and morphology, and facilitate the interactions of the target with the electrode surface. Under optimal operating conditions, differential pulse voltammetry demonstrated a remarkable feature: a broad linear working range of 10 to 140 μM, a detection limit of 0.14 μM, and a high sensitivity of 1.995 μA μM<sup>−1</sup> cm<sup>−2</sup>. The suggested method’s satisfactory sensitivity, along with its good stability, repeatability, and reproducibility, strongly point to a possible use for identifying quinine in real samples.
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publishDate 2024-10-01
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series Electrochem
spelling doaj-art-a0b08dc2b71342e3ba18cf4b2efe442e2025-08-20T02:53:43ZengMDPI AGElectrochem2673-32932024-10-015440742010.3390/electrochem5040027Pseudospherical Bismuth Oxychloride-Modified Carbon Paste Electrode for the Determination of Quinine in BeveragesTijana Mutić0Vesna Stanković1Miloš Ognjanović2Vladimir B. Nikolić3Guanyue Gao4Neso Sojic5Dalibor Stanković6Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, SerbiaInstitute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, SerbiaVinča Institute of Nuclear Sciences, University of Belgrade, Mike Petrovića Alasa 12–14, 11000 Belgrade, SerbiaFaculty of Chemistry, University of Belgrade, Studentski trg 12–16, 11000 Belgrade, SerbiaKey Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, ChinaInstitut des Sciences Moléculaires, University of Bordeaux, CNRS, Bordeaux INP, UMR 5255, 33607 Pessac, FranceFaculty of Chemistry, University of Belgrade, Studentski trg 12–16, 11000 Belgrade, SerbiaThe extensive use of the alkaloid quinine (QN) in the cosmetic and food industries has induced major concerns relating to its impact on human health, considering its potential toxicity. Therefore, developing sensitive and selective electrochemical sensors is crucial for monitoring QN in environmental, food, and pharmaceutical samples. To respond to this need, a surfactant-supported green synthesis approach, based on a straightforward, organic solvent-free hydrothermal method was employed to synthesize highly crystalline pseudospherical bismuth oxychloride (BiOCl) nanoparticles. This material was used for the enrichment of carbon paste electrodes and its further utilization for the detection and quantification of quinine. They have superior electrocatalytic performance, due to their size and morphology, and facilitate the interactions of the target with the electrode surface. Under optimal operating conditions, differential pulse voltammetry demonstrated a remarkable feature: a broad linear working range of 10 to 140 μM, a detection limit of 0.14 μM, and a high sensitivity of 1.995 μA μM<sup>−1</sup> cm<sup>−2</sup>. The suggested method’s satisfactory sensitivity, along with its good stability, repeatability, and reproducibility, strongly point to a possible use for identifying quinine in real samples.https://www.mdpi.com/2673-3293/5/4/27electrochemical sensorcarbon paste electrodenanomaterialsmalariaalkaloids
spellingShingle Tijana Mutić
Vesna Stanković
Miloš Ognjanović
Vladimir B. Nikolić
Guanyue Gao
Neso Sojic
Dalibor Stanković
Pseudospherical Bismuth Oxychloride-Modified Carbon Paste Electrode for the Determination of Quinine in Beverages
Electrochem
electrochemical sensor
carbon paste electrode
nanomaterials
malaria
alkaloids
title Pseudospherical Bismuth Oxychloride-Modified Carbon Paste Electrode for the Determination of Quinine in Beverages
title_full Pseudospherical Bismuth Oxychloride-Modified Carbon Paste Electrode for the Determination of Quinine in Beverages
title_fullStr Pseudospherical Bismuth Oxychloride-Modified Carbon Paste Electrode for the Determination of Quinine in Beverages
title_full_unstemmed Pseudospherical Bismuth Oxychloride-Modified Carbon Paste Electrode for the Determination of Quinine in Beverages
title_short Pseudospherical Bismuth Oxychloride-Modified Carbon Paste Electrode for the Determination of Quinine in Beverages
title_sort pseudospherical bismuth oxychloride modified carbon paste electrode for the determination of quinine in beverages
topic electrochemical sensor
carbon paste electrode
nanomaterials
malaria
alkaloids
url https://www.mdpi.com/2673-3293/5/4/27
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