Circulating tumour cell clusters: isolation, biological significance and therapeutic implications

Circulating tumour cell clusters: isolation, biological significance and therapeutic implications

Circulating tumour cells (CTCs) and CTC clusters are considered metastatic precursors due to their ability to seed distant metastasis. However, navigating the bloodstream presents a significant challenge for CTCs, as they must endure fluid shear forces and resist detachment-induced anoikis. Conseque...

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Main Authors: Jianglin Zhang, Xin Hong, Qingfeng Chen, Xuefei Liu, Yufan Yang, Guanyin Huang, Jingru Lian, Chunhao Long, Boxi Zhao, Binyu Zhang, Weijian Ye, Junhao Chen, Longxiang Du, Zhuofeng Jiang, Jialing Liu, Chengzhi Hu
Format: Article
Language:English
Published: BMJ Publishing Group 2024-09-01
Series:BMJ Oncology
Online Access:https://bmjoncology.bmj.com/content/3/1/e000437.full
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