Summary measures in non-inferiority clinical trials with a time-to-event outcome: an empirical comparison of power
Abstract Background Time-to-event data is commonly used in non-inferiority clinical trials. While the hazard ratio is a popular summary measure in this context, the difference in restricted mean survival time has been theoretically shown to increase power and interpretability. This study aimed to em...
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| Main Authors: | S. D. Lana Broer, Ian R. White, Tim P. Morris, Isabelle R. Weir, Marta Fiocco, Matteo Quartagno |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12874-025-02576-4 |
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