Effect of the Independent Acid Base Variables on Anion Gap Variation in Cardiac Surgical Patients: A Stewart-Figge Approach
Purpose. To determine the effect of each of independent acid base variables on the anion gap (AG) value in cardiac surgical patients. Methods. This retrospective study involved 128 cardiac surgical patients admitted for postoperative care. The variation of AG (AGvar) between the day of admission and...
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/907521 |
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| author | Michalis Agrafiotis Ilias Keklikoglou Sofia Papoti George Diminikos Konstantinos Diplaris Vassileios Michaelidis |
| author_facet | Michalis Agrafiotis Ilias Keklikoglou Sofia Papoti George Diminikos Konstantinos Diplaris Vassileios Michaelidis |
| author_sort | Michalis Agrafiotis |
| collection | DOAJ |
| description | Purpose. To determine the effect of each of independent acid base variables on the anion gap (AG) value in cardiac surgical patients. Methods. This retrospective study involved 128 cardiac surgical patients admitted for postoperative care. The variation of AG (AGvar) between the day of admission and the first postoperative day was correlated via a multiple linear regression model with the respective variations of the independent acid base variables, that is, apparent strong ion difference (SIDa), strong ion gap (SIG), carbon dioxide (PCO2), and albumin and phosphate concentrations. Results. The variations of all the above variables contributed significantly to the prediction of AGvar (adjusted R2=0.9999, F=201890.24, and P<0.001). According to the standardized coefficients (β), SIGvar (β = 0.948, P<0.001), [Albumin]var (β = 0.260, P<0.001), and [Phosphate]var (β = 0.191, P<0.001) were the major determinants of AGvar with lesser contributions from SIDa, var (β = 0.071, P<0.001) and PCO2, var (β = −0.067, P<0.001). Conclusions. All the independent acid base variables contribute to the prediction of the AG value. However, albumin and phosphate and SIG variations seem to be the most important predictors, while AG appears to be rather stable with changes in PCO2 and SIDa. |
| format | Article |
| id | doaj-art-a0a3b236205341a5b745362008f4e913 |
| institution | OA Journals |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
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| series | The Scientific World Journal |
| spelling | doaj-art-a0a3b236205341a5b745362008f4e9132025-08-20T02:20:55ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/907521907521Effect of the Independent Acid Base Variables on Anion Gap Variation in Cardiac Surgical Patients: A Stewart-Figge ApproachMichalis Agrafiotis0Ilias Keklikoglou1Sofia Papoti2George Diminikos3Konstantinos Diplaris4Vassileios Michaelidis52nd Department of Intensive Care Medicine, “G. Papanikolaou” General Hospital of Thessaloniki, G. Papanikolaou Avenue, Exohi, 57010 Thessaloniki, Greece2nd Department of Intensive Care Medicine, “G. Papanikolaou” General Hospital of Thessaloniki, G. Papanikolaou Avenue, Exohi, 57010 Thessaloniki, Greece2nd Department of Intensive Care Medicine, “G. Papanikolaou” General Hospital of Thessaloniki, G. Papanikolaou Avenue, Exohi, 57010 Thessaloniki, Greece2nd Department of Intensive Care Medicine, “G. Papanikolaou” General Hospital of Thessaloniki, G. Papanikolaou Avenue, Exohi, 57010 Thessaloniki, GreeceDepartment of Cardiothoracic Surgery, “G. Papanikolaou” General Hospital of Thessaloniki, G. Papanikolaou Avenue, Exohi, 57010 Thessaloniki, Greece2nd Department of Intensive Care Medicine, “G. Papanikolaou” General Hospital of Thessaloniki, G. Papanikolaou Avenue, Exohi, 57010 Thessaloniki, GreecePurpose. To determine the effect of each of independent acid base variables on the anion gap (AG) value in cardiac surgical patients. Methods. This retrospective study involved 128 cardiac surgical patients admitted for postoperative care. The variation of AG (AGvar) between the day of admission and the first postoperative day was correlated via a multiple linear regression model with the respective variations of the independent acid base variables, that is, apparent strong ion difference (SIDa), strong ion gap (SIG), carbon dioxide (PCO2), and albumin and phosphate concentrations. Results. The variations of all the above variables contributed significantly to the prediction of AGvar (adjusted R2=0.9999, F=201890.24, and P<0.001). According to the standardized coefficients (β), SIGvar (β = 0.948, P<0.001), [Albumin]var (β = 0.260, P<0.001), and [Phosphate]var (β = 0.191, P<0.001) were the major determinants of AGvar with lesser contributions from SIDa, var (β = 0.071, P<0.001) and PCO2, var (β = −0.067, P<0.001). Conclusions. All the independent acid base variables contribute to the prediction of the AG value. However, albumin and phosphate and SIG variations seem to be the most important predictors, while AG appears to be rather stable with changes in PCO2 and SIDa.http://dx.doi.org/10.1155/2014/907521 |
| spellingShingle | Michalis Agrafiotis Ilias Keklikoglou Sofia Papoti George Diminikos Konstantinos Diplaris Vassileios Michaelidis Effect of the Independent Acid Base Variables on Anion Gap Variation in Cardiac Surgical Patients: A Stewart-Figge Approach The Scientific World Journal |
| title | Effect of the Independent Acid Base Variables on Anion Gap Variation in Cardiac Surgical Patients: A Stewart-Figge Approach |
| title_full | Effect of the Independent Acid Base Variables on Anion Gap Variation in Cardiac Surgical Patients: A Stewart-Figge Approach |
| title_fullStr | Effect of the Independent Acid Base Variables on Anion Gap Variation in Cardiac Surgical Patients: A Stewart-Figge Approach |
| title_full_unstemmed | Effect of the Independent Acid Base Variables on Anion Gap Variation in Cardiac Surgical Patients: A Stewart-Figge Approach |
| title_short | Effect of the Independent Acid Base Variables on Anion Gap Variation in Cardiac Surgical Patients: A Stewart-Figge Approach |
| title_sort | effect of the independent acid base variables on anion gap variation in cardiac surgical patients a stewart figge approach |
| url | http://dx.doi.org/10.1155/2014/907521 |
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