Establishment of an RPA-CRISPR/Cas12a combined diagnostic system for Pneumocystis jirovecii pneumonia.

Establishment of an RPA-CRISPR/Cas12a combined diagnostic system for Pneumocystis jirovecii pneumonia.

Pneumocystis jirovecii causes severe pneumonia in immunocompromised individuals, leading to high mortality and an economic burden. There is a need for early detection methods suitable for low-resource settings and rapid point-of-care diagnostics. This study developed a detection method using Recombi...

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Bibliographic Details
Main Authors: Yun Wu, Yuhan Shao, Wei Li, Ying Yu, Xia Rao, Jingyi Li, Nicholas R Waterfield, Guowei Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012922
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