RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW

The aim of this study were to develop a radionuclide method for quantitative estimation of the myocardial blood flow (MBF). Twelve patients with suspected coronary artery disease underwent both Tc-99mmethoxyisobutylisonitrile (MIBI) imaging and coronary arterial injection of Tc-99m-radioalbumin macr...

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Main Authors: N. G. Krivonogov, S. M. Minin, A. L. Krylov, Yu. B. Lishmanov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2013-06-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/346
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author N. G. Krivonogov
S. M. Minin
A. L. Krylov
Yu. B. Lishmanov
author_facet N. G. Krivonogov
S. M. Minin
A. L. Krylov
Yu. B. Lishmanov
author_sort N. G. Krivonogov
collection DOAJ
description The aim of this study were to develop a radionuclide method for quantitative estimation of the myocardial blood flow (MBF). Twelve patients with suspected coronary artery disease underwent both Tc-99mmethoxyisobutylisonitrile (MIBI) imaging and coronary arterial injection of Tc-99m-radioalbumin macroaggregates (MAA). The myocardial uptake and MBF obtained using radionuclide angiocardiography and relative distributions of Tc-99m-MIBI were compared with the obtained using whole body with MAA as the gold standard. The myocardial uptake and MBF measured by MIBI imaging showed a good linear correlation with the myocardial uptake and MBF measured by MAA. These results indicate that MBF may be estimated by Tc-99m-MIBI imaging and can be used for the early detection and estimation of the functional severity of coronary lesions.
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issn 1682-0363
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publisher Siberian State Medical University (Tomsk)
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series Бюллетень сибирской медицины
spelling doaj-art-a09787ede24447ba88e79420bfa2b4ac2025-08-20T03:02:25ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842013-06-0112311111610.20538/1682-0363-2013-3-111-116342RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOWN. G. Krivonogov0S. M. Minin1A. L. Krylov2Yu. B. Lishmanov3Institute of Cardiology of SB RAMS, TomskInstitute of Cardiology of SB RAMS, TomskInstitute of Cardiology of SB RAMS, TomskInstitute of Cardiology of SB RAMS, TomskThe aim of this study were to develop a radionuclide method for quantitative estimation of the myocardial blood flow (MBF). Twelve patients with suspected coronary artery disease underwent both Tc-99mmethoxyisobutylisonitrile (MIBI) imaging and coronary arterial injection of Tc-99m-radioalbumin macroaggregates (MAA). The myocardial uptake and MBF obtained using radionuclide angiocardiography and relative distributions of Tc-99m-MIBI were compared with the obtained using whole body with MAA as the gold standard. The myocardial uptake and MBF measured by MIBI imaging showed a good linear correlation with the myocardial uptake and MBF measured by MAA. These results indicate that MBF may be estimated by Tc-99m-MIBI imaging and can be used for the early detection and estimation of the functional severity of coronary lesions.https://bulletin.ssmu.ru/jour/article/view/346coronary artery diseaseradionuclide imagingmyocardial blood flowtc-99-mibitc-99m-radioalbumin macroaggregates
spellingShingle N. G. Krivonogov
S. M. Minin
A. L. Krylov
Yu. B. Lishmanov
RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW
Бюллетень сибирской медицины
coronary artery disease
radionuclide imaging
myocardial blood flow
tc-99-mibi
tc-99m-radioalbumin macroaggregates
title RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW
title_full RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW
title_fullStr RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW
title_full_unstemmed RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW
title_short RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW
title_sort radionuclide quantitative in assessment of myocardial blood flow
topic coronary artery disease
radionuclide imaging
myocardial blood flow
tc-99-mibi
tc-99m-radioalbumin macroaggregates
url https://bulletin.ssmu.ru/jour/article/view/346
work_keys_str_mv AT ngkrivonogov radionuclidequantitativeinassessmentofmyocardialbloodflow
AT smminin radionuclidequantitativeinassessmentofmyocardialbloodflow
AT alkrylov radionuclidequantitativeinassessmentofmyocardialbloodflow
AT yublishmanov radionuclidequantitativeinassessmentofmyocardialbloodflow