RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW

The aim of this study were to develop a radionuclide method for quantitative estimation of the myocardial blood flow (MBF). Twelve patients with suspected coronary artery disease underwent both Tc-99mmethoxyisobutylisonitrile (MIBI) imaging and coronary arterial injection of Tc-99m-radioalbumin macr...

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Bibliographic Details
Main Authors: N. G. Krivonogov, S. M. Minin, A. L. Krylov, Yu. B. Lishmanov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2013-06-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/346
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Summary:The aim of this study were to develop a radionuclide method for quantitative estimation of the myocardial blood flow (MBF). Twelve patients with suspected coronary artery disease underwent both Tc-99mmethoxyisobutylisonitrile (MIBI) imaging and coronary arterial injection of Tc-99m-radioalbumin macroaggregates (MAA). The myocardial uptake and MBF obtained using radionuclide angiocardiography and relative distributions of Tc-99m-MIBI were compared with the obtained using whole body with MAA as the gold standard. The myocardial uptake and MBF measured by MIBI imaging showed a good linear correlation with the myocardial uptake and MBF measured by MAA. These results indicate that MBF may be estimated by Tc-99m-MIBI imaging and can be used for the early detection and estimation of the functional severity of coronary lesions.
ISSN:1682-0363
1819-3684