Decreased serum and local GPX4 and SLC7A11 expression correlates with disease severity in non-traumatic osteonecrosis of the femoral head

Abstract Background Ferroptosis is implicated in various musculoskeletal conditions, including non-traumatic osteonecrosis of the femoral head (NT-ONFH). Objective The objective of this study was to explore the levels of two crucial proteins associated with ferroptosis, namely Glutathione peroxidase...

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Bibliographic Details
Main Authors: Qing-He Ye, Peng Zhang, Yong-Heng Zhao, Wen-Xiu Zhu, Hong-Xun Zhu, Biao-Fang Wei
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Orthopaedic Surgery and Research
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Online Access:https://doi.org/10.1186/s13018-025-05912-y
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