Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot study

Background Treating depressed atrophic scars, which can result from various causes like post-trauma, acne vulgaris, and varicella, can be challenging. Still, there are several therapeutic modalities available that can help improve their appearance. Developing a method that is easy, safe, and effecti...

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Main Authors: Sudhir Singh, Adarsh L. Singh, Deepika Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of the Egyptian Women’s Dermatologic Society
Subjects:
Online Access:https://journals.lww.com/10.4103/jewd.jewd_5_24
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author Sudhir Singh
Adarsh L. Singh
Deepika Singh
author_facet Sudhir Singh
Adarsh L. Singh
Deepika Singh
author_sort Sudhir Singh
collection DOAJ
description Background Treating depressed atrophic scars, which can result from various causes like post-trauma, acne vulgaris, and varicella, can be challenging. Still, there are several therapeutic modalities available that can help improve their appearance. Developing a method that is easy, safe, and effective in treating depressed scars is a significant goal in dermatology and aesthetics. Objective To assess the efficacy of autologous dermal tissue transplantation in correcting atrophic scars due to trauma, acne vulgaris, varicella infection, and other inflammatory diseases and to evaluate any side effects associated with the procedure. Patients and methods Eleven patients with depressed atrophic scars willing to undergo the procedure were selected. Dermal tissue harvested after removing the epidermis by dermabrasion, was cut into small pieces, and inserted in the dermis of the recipient site with the help of 18 G needle. 2 experienced dermatologists did assessment of results by using clinical assessment scores. Results Out of 11 patients, one patient showed a 25–50% improvement, six patients showed improvement between 51 and 75%, and four patients showed more than 75% improvement. Improvement was good in small linear scars. Milia-like lesion developed in one patient. Conclusion Autologous dermal tissue transplantation is effective in depressed scars. The technique is safe, cheap, and can be mastered easily. It is important to continue conducting research and clinical trials to establish the benefits and limitations of autologous dermal tissue transplantation for depressed scars. Additionally, long-term follow-up studies can provide insights into the durability of the treatment results.
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spelling doaj-art-a0947184a94742bf90cb7efd3ac1abdc2025-01-20T04:38:32ZengWolters Kluwer Medknow PublicationsJournal of the Egyptian Women’s Dermatologic Society2090-25652025-01-01221475110.4103/jewd.jewd_5_24Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot studySudhir SinghAdarsh L. SinghDeepika SinghBackground Treating depressed atrophic scars, which can result from various causes like post-trauma, acne vulgaris, and varicella, can be challenging. Still, there are several therapeutic modalities available that can help improve their appearance. Developing a method that is easy, safe, and effective in treating depressed scars is a significant goal in dermatology and aesthetics. Objective To assess the efficacy of autologous dermal tissue transplantation in correcting atrophic scars due to trauma, acne vulgaris, varicella infection, and other inflammatory diseases and to evaluate any side effects associated with the procedure. Patients and methods Eleven patients with depressed atrophic scars willing to undergo the procedure were selected. Dermal tissue harvested after removing the epidermis by dermabrasion, was cut into small pieces, and inserted in the dermis of the recipient site with the help of 18 G needle. 2 experienced dermatologists did assessment of results by using clinical assessment scores. Results Out of 11 patients, one patient showed a 25–50% improvement, six patients showed improvement between 51 and 75%, and four patients showed more than 75% improvement. Improvement was good in small linear scars. Milia-like lesion developed in one patient. Conclusion Autologous dermal tissue transplantation is effective in depressed scars. The technique is safe, cheap, and can be mastered easily. It is important to continue conducting research and clinical trials to establish the benefits and limitations of autologous dermal tissue transplantation for depressed scars. Additionally, long-term follow-up studies can provide insights into the durability of the treatment results.https://journals.lww.com/10.4103/jewd.jewd_5_24atrophic scarsautologous dermal transplantationpost acne scarpost-traumatic scar
spellingShingle Sudhir Singh
Adarsh L. Singh
Deepika Singh
Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot study
Journal of the Egyptian Women’s Dermatologic Society
atrophic scars
autologous dermal transplantation
post acne scar
post-traumatic scar
title Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot study
title_full Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot study
title_fullStr Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot study
title_full_unstemmed Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot study
title_short Analysis of restoration in atrophic scar by intradermal autologous dermal tissue: a pilot study
title_sort analysis of restoration in atrophic scar by intradermal autologous dermal tissue a pilot study
topic atrophic scars
autologous dermal transplantation
post acne scar
post-traumatic scar
url https://journals.lww.com/10.4103/jewd.jewd_5_24
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AT adarshlsingh analysisofrestorationinatrophicscarbyintradermalautologousdermaltissueapilotstudy
AT deepikasingh analysisofrestorationinatrophicscarbyintradermalautologousdermaltissueapilotstudy