A retrospective efficacy and safety study of pembrolizumab/cetuximab neoadjuvant therapy in locally advanced hypopharyngeal cancer

A retrospective efficacy and safety study of pembrolizumab/cetuximab neoadjuvant therapy in locally advanced hypopharyngeal cancer

PurposeThe primary objective of this study was to retrospectively assess the efficacy and safety profiles of two neoadjuvant regimens combining either pembrolizumab or cetuximab with paclitaxel and cisplatin in patients with locally advanced hypopharyngeal cancer (LAHPC).MethodsLAHPC patients who re...

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Bibliographic Details
Main Authors: Guangnan Yao, Xiaobo Wu, Hanqing Lin, Zhihong Chen, Chang Lin, Gongbiao Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
hypopharyngeal cancer
neoadjuvant therapy
pembrolizumab
cetuximab
minimally invasive surgery
organ preservation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574988/full
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