A small heat shock protein Fmp28 influences virulence by regulating Als3 expression via the cAMP-PKA signaling pathway in Candida albicans

A small heat shock protein Fmp28 influences virulence by regulating Als3 expression via the cAMP-PKA signaling pathway in Candida albicans

ABSTRACT Small heat shock proteins are evolutionarily conserved molecular chaperones with diverse cellular roles. However, our understanding of their functions in pathogenic microorganisms remains limited. In this study, we identified and characterized Fmp28, a novel small heat shock protein that en...

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Main Authors: Junjun Tan, Qiong Liu, Zhiping Liu, Yanli Cao, Xiaomin Yu, Qianjun Zhao, Niya Hu, Yanling Liu, Yuwei Wan, Yeming Zhang, Huizhen Tian, Lingbing Zeng, Xiaotian Huang
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mBio
Subjects:
small heat shock protein
Fmp28
Candida albicans
Als3
virulence
Online Access:https://journals.asm.org/doi/10.1128/mbio.01253-25
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