Vitamin D and autoimmune diseases
Vitamin D and its deficiency are becoming a subject of great interest in recent years. In addition to the well-known role of vitamin D in maintaining bone health, evidence from recent years are accumulating in favor of its importance in the functioning of the immune system. The association between v...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2017-01-01
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| Series: | Indian Journal of Rheumatology |
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| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=4;spage=219;epage=222;aulast=Azrielant |
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| _version_ | 1832569141233451008 |
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| author | Shir Azrielant Yehuda Shoenfeld |
| author_facet | Shir Azrielant Yehuda Shoenfeld |
| author_sort | Shir Azrielant |
| collection | DOAJ |
| description | Vitamin D and its deficiency are becoming a subject of great interest in recent years. In addition to the well-known role of vitamin D in maintaining bone health, evidence from recent years are accumulating in favor of its importance in the functioning of the immune system. The association between vitamin D deficiency and autoimmune diseases has been supported by epidemiological studies, demonstrating higher prevalence of vitamin D deficiency among autoimmune patients, in comparison to the general population. Vitamin D was also associated to various autoimmune diseases in both molecular and interventional studies; among the associated diseases are: systemic lupus erythematosus, type 1 diabetes mellitus, multiple sclerosis and others. In this review, relevant literature on the association between autoimmunity and vitamin D deficiency will be reviewed and discussed, as well as a summary of important recommendations for vitamin D supplementations in autoimmune patients. |
| format | Article |
| id | doaj-art-a08509ea59034b85b94bc0497b6e8662 |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-a08509ea59034b85b94bc0497b6e86622025-02-02T23:16:29ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012017-01-0112421922210.4103/injr.injr_99_17Vitamin D and autoimmune diseasesShir AzrielantYehuda ShoenfeldVitamin D and its deficiency are becoming a subject of great interest in recent years. In addition to the well-known role of vitamin D in maintaining bone health, evidence from recent years are accumulating in favor of its importance in the functioning of the immune system. The association between vitamin D deficiency and autoimmune diseases has been supported by epidemiological studies, demonstrating higher prevalence of vitamin D deficiency among autoimmune patients, in comparison to the general population. Vitamin D was also associated to various autoimmune diseases in both molecular and interventional studies; among the associated diseases are: systemic lupus erythematosus, type 1 diabetes mellitus, multiple sclerosis and others. In this review, relevant literature on the association between autoimmunity and vitamin D deficiency will be reviewed and discussed, as well as a summary of important recommendations for vitamin D supplementations in autoimmune patients.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=4;spage=219;epage=222;aulast=AzrielantAutoimmunitymultiple sclerosissystemic lupus erythematosustype 1 diabetes mellitusVitamin D |
| spellingShingle | Shir Azrielant Yehuda Shoenfeld Vitamin D and autoimmune diseases Indian Journal of Rheumatology Autoimmunity multiple sclerosis systemic lupus erythematosus type 1 diabetes mellitus Vitamin D |
| title | Vitamin D and autoimmune diseases |
| title_full | Vitamin D and autoimmune diseases |
| title_fullStr | Vitamin D and autoimmune diseases |
| title_full_unstemmed | Vitamin D and autoimmune diseases |
| title_short | Vitamin D and autoimmune diseases |
| title_sort | vitamin d and autoimmune diseases |
| topic | Autoimmunity multiple sclerosis systemic lupus erythematosus type 1 diabetes mellitus Vitamin D |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=4;spage=219;epage=222;aulast=Azrielant |
| work_keys_str_mv | AT shirazrielant vitamindandautoimmunediseases AT yehudashoenfeld vitamindandautoimmunediseases |