Modeling tumor relapse using proliferation tracing and ablation transgenic mouse
Abstract Tumor relapse remains a significant obstacle to successful therapy. Preclinical animal models that accurately reflect tumor relapse in patients are urgently needed. Here, we employed a dual recombinase-mediated genetic system to genetically trace and ablate proliferating cells in a polyomav...
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| Main Authors: | Chuang Zhao, Xin-nan Zheng, Han-ying Huang, Lin Tian |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | npj Breast Cancer |
| Online Access: | https://doi.org/10.1038/s41523-025-00792-1 |
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