New Temporin A Analogues Modified in Positions 1 and 10—Synthesis and Biological Studies

New Temporin A Analogues Modified in Positions 1 and 10—Synthesis and Biological Studies

<b>Background/Objectives</b>: With growing antimicrobial resistance, the overuse of antibiotics, and stagnation in the discovery of new antibiotics, a novel alternative is required to overcome hard-to-treat infections. Antimicrobial peptides (AMPs) show great potential as a possible alte...

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Bibliographic Details
Main Authors: Dilyana Dimitrova, Veronica Nemska, Ivan Iliev, Stoyko Petrin, Nelly Georgieva, Dancho Danalev
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
Subjects:
antimicrobial peptides
Temporin A
antimicrobial activity
antiproliferative activity
cytotoxicity
phototoxicity
Online Access:https://www.mdpi.com/1999-4923/17/4/396
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