A fatal case of fulminant myocarditis caused by influenza A virus
Introduction. Myocarditis is defined as an inflammation of a heart muscle, which can be caused by a number of agents, among which viruses are the most common. Fulminant myocarditis is a rapidly progressive, life-threatening myocarditis, followed by the development of cardiogenic shock. Among viruses...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2019-01-01
|
| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800017K.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850241198859485184 |
|---|---|
| author | Kovačević Mila Srdanović Ilija Jaraković Milana Bogdanović Dragana Čanković Milenko |
| author_facet | Kovačević Mila Srdanović Ilija Jaraković Milana Bogdanović Dragana Čanković Milenko |
| author_sort | Kovačević Mila |
| collection | DOAJ |
| description | Introduction. Myocarditis is defined as an inflammation of a heart muscle, which can be caused by a number of agents, among which viruses are the most common. Fulminant myocarditis is a rapidly progressive, life-threatening myocarditis, followed by the development of cardiogenic shock. Among viruses, there are a number of common ones, but according to our knowledge, there are only a few cases of fulminant myocarditis caused by influenza A virus described in the literature. Case report. We presented a 44-year-old man who was admitted to the Cardiology Intensive Care Unit because of the clinical as well as electrocardiographic signs pointing to the STsegment elevated myocardial infarction with peracute development of heart failure and cardiogenic shock and subsequently lethal outcome, despite applied circulatory support. The urgent coronarography showed no signs of coronary artery disease, while the autopsy revealed myocarditis and the realtime polymerase chain reaction of nasopharyngeal swab revealed influenza A(H3) virus. Conclusion. Fulminant myocarditis is a life-threatening cardiac disease which should be treated in Intensive Care Units with both medicament and mechanical circulatory support and antiviral therapy and which, despite the applied therapy, has a high mortality rate. Influenza A virus is a rare cause of fulminant myocarditis which should be taken into consideration. |
| format | Article |
| id | doaj-art-a05201bb79284e2eb6df3d723f842010 |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-a05201bb79284e2eb6df3d723f8420102025-08-20T02:00:39ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202019-01-0176121290129610.2298/VSP170928017K0042-84501800017KA fatal case of fulminant myocarditis caused by influenza A virusKovačević Mila0Srdanović Ilija1Jaraković Milana2Bogdanović Dragana3Čanković Milenko4Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, SerbiaInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, SerbiaInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia Introduction. Myocarditis is defined as an inflammation of a heart muscle, which can be caused by a number of agents, among which viruses are the most common. Fulminant myocarditis is a rapidly progressive, life-threatening myocarditis, followed by the development of cardiogenic shock. Among viruses, there are a number of common ones, but according to our knowledge, there are only a few cases of fulminant myocarditis caused by influenza A virus described in the literature. Case report. We presented a 44-year-old man who was admitted to the Cardiology Intensive Care Unit because of the clinical as well as electrocardiographic signs pointing to the STsegment elevated myocardial infarction with peracute development of heart failure and cardiogenic shock and subsequently lethal outcome, despite applied circulatory support. The urgent coronarography showed no signs of coronary artery disease, while the autopsy revealed myocarditis and the realtime polymerase chain reaction of nasopharyngeal swab revealed influenza A(H3) virus. Conclusion. Fulminant myocarditis is a life-threatening cardiac disease which should be treated in Intensive Care Units with both medicament and mechanical circulatory support and antiviral therapy and which, despite the applied therapy, has a high mortality rate. Influenza A virus is a rare cause of fulminant myocarditis which should be taken into consideration.http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800017K.pdfdiagnosisinfluenza a virusinfluenza, humanmyocarditisshock, cardiogenictreatment outcome |
| spellingShingle | Kovačević Mila Srdanović Ilija Jaraković Milana Bogdanović Dragana Čanković Milenko A fatal case of fulminant myocarditis caused by influenza A virus Vojnosanitetski Pregled diagnosis influenza a virus influenza, human myocarditis shock, cardiogenic treatment outcome |
| title | A fatal case of fulminant myocarditis caused by influenza A virus |
| title_full | A fatal case of fulminant myocarditis caused by influenza A virus |
| title_fullStr | A fatal case of fulminant myocarditis caused by influenza A virus |
| title_full_unstemmed | A fatal case of fulminant myocarditis caused by influenza A virus |
| title_short | A fatal case of fulminant myocarditis caused by influenza A virus |
| title_sort | fatal case of fulminant myocarditis caused by influenza a virus |
| topic | diagnosis influenza a virus influenza, human myocarditis shock, cardiogenic treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800017K.pdf |
| work_keys_str_mv | AT kovacevicmila afatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT srdanovicilija afatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT jarakovicmilana afatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT bogdanovicdragana afatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT cankovicmilenko afatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT kovacevicmila fatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT srdanovicilija fatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT jarakovicmilana fatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT bogdanovicdragana fatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus AT cankovicmilenko fatalcaseoffulminantmyocarditiscausedbyinfluenzaavirus |