Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage Repair

<i>Background and Objectives</i>: Chondral and osteochondral lesions can lead to osteoarthritis if untreated, making accurate assessment of cartilage repair outcomes essential for optimizing treatment strategies. The objective of this study was to compare MOCART and MOCART 2.0 and to eva...

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Main Authors: Felix Conrad Oettl, Louis Leuthard, Moritz Brunner, Vincent A. Stadelmann, Stefan Preiss, Michael Leunig, Gian M. Salzmann, Jakob Hax
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Medicina
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Online Access:https://www.mdpi.com/1648-9144/61/4/745
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author Felix Conrad Oettl
Louis Leuthard
Moritz Brunner
Vincent A. Stadelmann
Stefan Preiss
Michael Leunig
Gian M. Salzmann
Jakob Hax
author_facet Felix Conrad Oettl
Louis Leuthard
Moritz Brunner
Vincent A. Stadelmann
Stefan Preiss
Michael Leunig
Gian M. Salzmann
Jakob Hax
author_sort Felix Conrad Oettl
collection DOAJ
description <i>Background and Objectives</i>: Chondral and osteochondral lesions can lead to osteoarthritis if untreated, making accurate assessment of cartilage repair outcomes essential for optimizing treatment strategies. The objective of this study was to compare MOCART and MOCART 2.0 and to evaluate the clinical utility of both across different surgical cartilage repair techniques and various time points. <i>Material and Methods</i>: This study included 111 patients (age: 35 ± 10, 35% female) who underwent cartilage repair surgery of the knee between September 2015 and March 2022. A total of 188 postoperative magnetic resonance images were evaluated using MOCART and MOCART 2.0. The correlations between both scores, as well as to the change in Patient-Reported Outcome Measures (PROMs), were determined. <i>Results</i>: MOCART 2.0 scores (66 ± 13) were significantly higher than MOCART scores (58 ± 13, <i>p</i> < 0.001). Positive correlation was observed between scoring systems (r = 0.837, <i>p</i> < 0.001). There was no significant correlation between MOCART or MOCART 2.0 scores and the change in PROMs. Noticeably, there was a statistically significant correlation between both MOCART and MOCART 2.0 in the AutoCart subgroup across multiple timepoints for the change in PROMs. <i>Conclusions</i>: Based on radiographic–clinical outcome discordance, clinicians should not rely solely on MOCART or MOCART 2.0 scores when evaluating cartilage repair success but instead prioritize patient-reported functional improvements while using imaging as a complementary assessment tool.
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spelling doaj-art-a04b4483f1bc4e5593f7879b0e04628f2025-08-20T03:13:52ZengMDPI AGMedicina1010-660X1648-91442025-04-0161474510.3390/medicina61040745Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage RepairFelix Conrad Oettl0Louis Leuthard1Moritz Brunner2Vincent A. Stadelmann3Stefan Preiss4Michael Leunig5Gian M. Salzmann6Jakob Hax7Department of Hip and Knee Surgery, Schulthess Klinik, 8008 Zurich, SwitzerlandDepartment of Research and Development, Schulthess Klinik, 8008 Zurich, SwitzerlandDepartment of Hip and Knee Surgery, Schulthess Klinik, 8008 Zurich, SwitzerlandDepartment of Research and Development, Schulthess Klinik, 8008 Zurich, SwitzerlandDepartment of Hip and Knee Surgery, Schulthess Klinik, 8008 Zurich, SwitzerlandDepartment of Hip and Knee Surgery, Schulthess Klinik, 8008 Zurich, SwitzerlandDepartment of Hip and Knee Surgery, Schulthess Klinik, 8008 Zurich, SwitzerlandDepartment of Hip and Knee Surgery, Schulthess Klinik, 8008 Zurich, Switzerland<i>Background and Objectives</i>: Chondral and osteochondral lesions can lead to osteoarthritis if untreated, making accurate assessment of cartilage repair outcomes essential for optimizing treatment strategies. The objective of this study was to compare MOCART and MOCART 2.0 and to evaluate the clinical utility of both across different surgical cartilage repair techniques and various time points. <i>Material and Methods</i>: This study included 111 patients (age: 35 ± 10, 35% female) who underwent cartilage repair surgery of the knee between September 2015 and March 2022. A total of 188 postoperative magnetic resonance images were evaluated using MOCART and MOCART 2.0. The correlations between both scores, as well as to the change in Patient-Reported Outcome Measures (PROMs), were determined. <i>Results</i>: MOCART 2.0 scores (66 ± 13) were significantly higher than MOCART scores (58 ± 13, <i>p</i> < 0.001). Positive correlation was observed between scoring systems (r = 0.837, <i>p</i> < 0.001). There was no significant correlation between MOCART or MOCART 2.0 scores and the change in PROMs. Noticeably, there was a statistically significant correlation between both MOCART and MOCART 2.0 in the AutoCart subgroup across multiple timepoints for the change in PROMs. <i>Conclusions</i>: Based on radiographic–clinical outcome discordance, clinicians should not rely solely on MOCART or MOCART 2.0 scores when evaluating cartilage repair success but instead prioritize patient-reported functional improvements while using imaging as a complementary assessment tool.https://www.mdpi.com/1648-9144/61/4/745cartilageMOCARTpatient-reported outcome measuresminced cartilageAutoCart and level of evidence
spellingShingle Felix Conrad Oettl
Louis Leuthard
Moritz Brunner
Vincent A. Stadelmann
Stefan Preiss
Michael Leunig
Gian M. Salzmann
Jakob Hax
Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage Repair
Medicina
cartilage
MOCART
patient-reported outcome measures
minced cartilage
AutoCart and level of evidence
title Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage Repair
title_full Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage Repair
title_fullStr Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage Repair
title_full_unstemmed Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage Repair
title_short Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage Repair
title_sort correlation and comparative evaluation of mocart and mocart 2 0 for assessing cartilage repair
topic cartilage
MOCART
patient-reported outcome measures
minced cartilage
AutoCart and level of evidence
url https://www.mdpi.com/1648-9144/61/4/745
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