Heterosynaptic plasticity-induced modulation of synapses
Abstract Plasticity is a common feature of synapses that is stated in different ways and occurs through several mechanisms. The regular action of the brain needs to be balanced in several neuronal and synaptic features, one of which is synaptic plasticity. The different homeostatic processes, includ...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Journal of Physiological Sciences |
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| Online Access: | https://doi.org/10.1186/s12576-023-00893-1 |
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| author | Masoumeh Kourosh-Arami Alireza Komaki Masoumeh Gholami Seyed Hossein Marashi Sara Hejazi |
| author_facet | Masoumeh Kourosh-Arami Alireza Komaki Masoumeh Gholami Seyed Hossein Marashi Sara Hejazi |
| author_sort | Masoumeh Kourosh-Arami |
| collection | DOAJ |
| description | Abstract Plasticity is a common feature of synapses that is stated in different ways and occurs through several mechanisms. The regular action of the brain needs to be balanced in several neuronal and synaptic features, one of which is synaptic plasticity. The different homeostatic processes, including the balance between excitation/inhibition or homeostasis of synaptic weights at the single-neuron level, may obtain this. Homosynaptic Hebbian-type plasticity causes associative alterations of synapses. Both homosynaptic and heterosynaptic plasticity characterize the corresponding aspects of adjustable synapses, and both are essential for the regular action of neural systems and their plastic synapses. In this review, we will compare homo- and heterosynaptic plasticity and the main factors affecting the direction of plastic changes. This review paper will also discuss the diverse functions of the different kinds of heterosynaptic plasticity and their properties. We argue that a complementary system of heterosynaptic plasticity demonstrates an essential cellular constituent for homeostatic modulation of synaptic weights and neuronal activity. Graphical Abstract |
| format | Article |
| id | doaj-art-a04b34c90a374d14b4ed9221affc4cad |
| institution | DOAJ |
| issn | 1880-6562 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Physiological Sciences |
| spelling | doaj-art-a04b34c90a374d14b4ed9221affc4cad2025-08-20T03:18:55ZengElsevierJournal of Physiological Sciences1880-65622023-12-0173111410.1186/s12576-023-00893-1Heterosynaptic plasticity-induced modulation of synapsesMasoumeh Kourosh-Arami0Alireza Komaki1Masoumeh Gholami2Seyed Hossein Marashi3Sara Hejazi4Department of Neuroscience, School of Advanced Technologies in Medicine, Iran University of Medical SciencesDepartment of Neuroscience, School of Science and Advanced Technologies in Medicine, Hamadan University of Medical SciencesDepartment of Physiology, Medical College, Arak University of Medical SciencesDepartment of Physiology, Medical College, Tarbiat Modares UniversityDepartment of Industrial Engineering & Management Systems, University of Central FloridaAbstract Plasticity is a common feature of synapses that is stated in different ways and occurs through several mechanisms. The regular action of the brain needs to be balanced in several neuronal and synaptic features, one of which is synaptic plasticity. The different homeostatic processes, including the balance between excitation/inhibition or homeostasis of synaptic weights at the single-neuron level, may obtain this. Homosynaptic Hebbian-type plasticity causes associative alterations of synapses. Both homosynaptic and heterosynaptic plasticity characterize the corresponding aspects of adjustable synapses, and both are essential for the regular action of neural systems and their plastic synapses. In this review, we will compare homo- and heterosynaptic plasticity and the main factors affecting the direction of plastic changes. This review paper will also discuss the diverse functions of the different kinds of heterosynaptic plasticity and their properties. We argue that a complementary system of heterosynaptic plasticity demonstrates an essential cellular constituent for homeostatic modulation of synaptic weights and neuronal activity. Graphical Abstracthttps://doi.org/10.1186/s12576-023-00893-1Heterosynaptic plasticityHomosynaptic plasticitySynaptic weightDynamics |
| spellingShingle | Masoumeh Kourosh-Arami Alireza Komaki Masoumeh Gholami Seyed Hossein Marashi Sara Hejazi Heterosynaptic plasticity-induced modulation of synapses Journal of Physiological Sciences Heterosynaptic plasticity Homosynaptic plasticity Synaptic weight Dynamics |
| title | Heterosynaptic plasticity-induced modulation of synapses |
| title_full | Heterosynaptic plasticity-induced modulation of synapses |
| title_fullStr | Heterosynaptic plasticity-induced modulation of synapses |
| title_full_unstemmed | Heterosynaptic plasticity-induced modulation of synapses |
| title_short | Heterosynaptic plasticity-induced modulation of synapses |
| title_sort | heterosynaptic plasticity induced modulation of synapses |
| topic | Heterosynaptic plasticity Homosynaptic plasticity Synaptic weight Dynamics |
| url | https://doi.org/10.1186/s12576-023-00893-1 |
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